Publications by authors named "Sharmila Murugesan"

Article Synopsis
  • The study focused on the medicinal plant L., traditionally used in Siddha and Ayurvedic medicine in India, assessing its various chemical properties across 99 different accessions.
  • The research measured total monomeric anthocyanin, flavonol, antioxidative potential, protein, and ash content using specific laboratory methods.
  • Findings revealed that a completely black accession had the highest anthocyanin and flavonol levels, while a white accession had the most protein; these results suggest potential applications in pharmaceutical drug development.
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Background Coronavirus disease 2019 (COVID-19), resulting from the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), has not only shown substantial effects on the respiratory system but also on extrapulmonary systems, including cardiovascular, gastrointestinal, hematological, and immune responses, notably spleen enlargement. The connection between the enlargement of the spleen and pulmonary complications in individuals with COVID-19 is still not well elucidated, with current studies offering divergent conclusions. Objective This study aims to elucidate the correlation between splenomegaly, as assessed by computed tomography (CT) imaging, and the extent of lung involvement (LI) in COVID-19 patients, thereby offering insights into potential prognostic indicators.

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Purpose: Optic neuritis (ON) is a relatively common ophthalmic disease that has recently received renewed attention owing to immunological breakthroughs. We studied the profile of patients with ON with special reference to antibody-mediated ON and the challenges faced in its management.

Methods: Case records of patients with ON presenting to a tertiary eye-care center in South India were analyzed.

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Occurrence of eclampsia before 20 weeks of pregnancy and after 48 hours of delivery in the absence of typical signs of hypertension and or proteinuria is termed as atypical eclampsia. Atypical or non-classic eclampsia will have some symptoms of eclampsia but without the usual proteinuria or hypertension. All patients with atypical onset should undergo neurological evaluation to rule out neurologic causes of seizures.

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