Unlabelled: Attenuation, photon scatter, and distance-dependent collimator-detector response are major degrading factors in myocardial SPECT images. The current study investigated whether compensation for these factors improves perfusion defect detectability, and compared the results for human observers with a previous study using a mathematical observer.
Methods: Four methods were investigated: attenuation compensation (AC); attenuation and detector response compensation; attenuation and scatter compensation; and attenuation, detector response, and scatter compensation (ADSC).