Publications by authors named "Sharlene S W Lee"
Article Synopsis
- Breast cancer in Malaysia shows a high occurrence in women under 50, with genetics playing a potential role that hasn't been fully explored across different ethnic groups.
- Researchers studied 37 individuals under 40 years old with early-onset breast cancer and no family history to identify BRCA1 and BRCA2 mutations through comprehensive sequencing.
- The study found 14 BRCA1 and 17 BRCA2 mutations, including 8 novel mutations, with 2.7% and 5.4% prevalence of deleterious mutations respectively, aligning with rates observed in other Asian populations.
