Publications by authors named "Sharleen Bowes"
Article Synopsis
- Eight new human polyomaviruses have been identified since 2007, with limited knowledge on their prevalence and tissue tropism for newer species like HPyV 6, 7, 9, TSPyV, and MWPyV.
- A study using real-time PCR tested various bodily fluids from both healthy individuals and those undergoing diagnostic testing, finding that novel polyomaviruses were primarily detected in respiratory swabs and feces.
- MWPyV was the most commonly found new polyomavirus, particularly in children, indicating potential for subclinical infections and more frequent detection in immunocompromised patients, while the other viruses were present at lower rates.
Background: HIV is the most important risk factor for progression of latent tuberculosis infection (LTBI) to active tuberculosis (TB). Detection and treatment of LTBI is necessary to reduce the increasing burden of TB in the UK, but a unified LTBI screening approach has not been adopted.
Objective: To compare the effectiveness of a TB risk-focused approach to LTBI screening in the HIV-positive population against current UK National Institute for Health and Clinical Excellence (NICE) guidance.