Endometrial hyperplasia - the dilemma of management remains: a retrospective observational study of 280 women.

Objective: To quantify the rate of inconsistency in histopathological reporting between endometrial biopsy specimens (obtained by Pipelle endometrial sampler or curettage) and hysterectomy specimens using the World Health Organization classification criteria.

Study Design: A retrospective review of the records of 280 women with a histopathological diagnosis of endometrial hyperplasia treated in Ipswich Hospital NHS Trust, UK from 1 January 1998 to 31 May 2009.

Results: Discrepancy was found between the histopathological results of endometrial samples and hysterectomy specimens.