Introduction: Reducing territorial inequalities in access to care and innovations in oncology is an objective of the ten-year strategy to fight cancer. The populations of Overseas Territories (OT) face limits in terms of access to clinical research in oncology (CRO).
Methods: The article aims to share an exhaustive inventory of the challenges observed in the development of CRO in the OT but also the means identified to respond to them, illustrated with recent successes in terms of setting up a CRO program.