Publications by authors named "Sharayu Magar"
Article Synopsis
- Jumbo phages, which have large genomes and unique life cycles, use a special structure to protect their DNA from host immune systems like CRISPR-Cas, but their overall genetic diversity and interactions with these systems need more exploration.* -
- Analysis of 331 jumbo phage genomes revealed that there are no universally conserved "core genes," but seven "soft-core genes" important for DNA functions were identified, highlighting the genetic variety among these viruses.* -
- The study also found that jumbo phages often exchange genes among themselves and with other viruses, suggesting a complex evolutionary history, and many can potentially evade host immunity through various mechanisms.*
Formulation of Dual-Functional Nonionic Cetomacrogol Creams Incorporated with Bacteriophage and Human Platelet Lysate for Effective Targeting of MDR and Enhanced Wound Healing.
Aarcha Shanmugha Mary Maruthupandy Muthuchamy Muneeswaran Thillaichidambaram Sinuk Lee Barath Sivaraj Sharayu Magar
ACS Appl Bio Mater
October 2024
Successful development of phage-based therapeutics and their utility predominantly depend on the mode and route of phage administration. Topical and site-directed phage application evokes minimal immune clearance and allows more phage-host adsorption, thereby ensuring higher phage efficacy. However, a notable drawback of conventional topical phage applications is the absence of sustained release.
View Article and Find Full Text PDFEndophytic sp. are recognized as a potential resource for valuable natural products but are less explored. This study focused on exploring endophytic species residing within tomato plants () harboring genes for the production of a novel class of antibiotics.
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