Profiling mRNA encoding glucocorticoid receptor α in saliva: Relationship to hair cortisol levels in individuals aged 15-25 years.

Objective: We assessed levels of mRNA encoding two glucocorticoid receptor (GR) isoforms (GRα and GRβ) in saliva and examined their relationship with hair cortisol levels and dental caries experience.

Design: Adolescents and young adults were assessed for dental caries experience, and hair cortisol was measured by ELISA. RNA was extracted from whole saliva using TRIzol, followed by quantitative real-time PCR analysis of GRα, GRβ, and glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

Comprehensive assessment of periodontal health in cerebral palsy: A systematic review and meta-analysis.

Aims: Cerebral palsy (CP) is the term for a set of neurological disorders resulting from brain damage that impairs motor function. The aim of the present study was to perform a systematic review of the literature to determine whether individuals with CP are at a greater risk of negative periodontal health outcomes compared to those without CP.

Methods: This study followed the recommendations of the MOOSE guidelines.

Relationships among Cortisol, Perceived Stress, and Dental Caries Experience in Adolescents and Young Adults.

Introduction: Stress can impact mental and physical health, especially during adolescence and young adulthood, but the extent of its contribution to dental caries is poorly understood. The present study assessed the association between perceived stress, cortisol levels (in hair and saliva), and overall caries experience of adolescents and young adults aged 15-25 years.

Methods: Hair and saliva samples were obtained from 93 participants free of periodontal disease.

Dental caries and developmental defects of enamel in cerebral palsy: A meta-analysis.

Objective: This systematic review and meta-analysis aimed to compare the occurrence of dental caries and developmental defects of enamel (DDE) in individuals with and without cerebral palsy (CP).

Materials And Methods: We conducted searches across five databases and the grey literature. Data were organized using EndNote 20.

The Impact of COVID-19 on Parental Perception of Oral Health-Related Quality of Life of Children: A Comparison of a Sample from Saudi Arabia and Kuwait.

Materials And Methods: OHRQoL was measured using a a validated Arabic version of the Child Oral Health Impact Profile (COHIP). Parents of children aged between 5 and 9 years were administered questionnaire during the COVID-19 pandemic. The responses were compared across the different domains of the questionnaire between the two countries using the Mann-Whitney test.

Intersection of the iADH undergraduate curriculum in special care dentistry and the association of Canadian faculties of dentistry competencies framework.

Aims: To map the International Association of Disability and Oral Health (iADH) curriculum to the Association of Canadian Faculties of Dentistry (ACFD) competencies framework to develop a strategy for teaching special care dentistry (SCD) using the International Classification of Functioning, Disability, and Health (ICF). To review the literature to identify educational methodologies that support teaching SCD competencies.

Methods: The 20 subdomains of the ACFD competencies framework were mapped to the 18 subdomains of the iADH competency matrix.

The Impact of COVID-19 on Dental Treatment in Kuwait-A Retrospective Analysis from the Nation's Largest Hospital.

Background: The COVID-19 pandemic has changed the way dentistry has been practiced the world over. This study sought to assess the impact of the COVID-19 pandemic on the patterns of attendance for dental treatment in a large hospital in Kuwait through comparisons with data from the year prior to the pandemic.

Methods: A total of 176,690 appointment records from 34,250 patients presenting to the AlJahra specialist hospital in Kuwait for dental treatment from April 2019 to March 2021 were analyzed.

COVID-19-Related School Closures and Caries Risk in Canadian Children.

Background: Despite increased efforts to improve the health of those with temporomandibular disorder (TMD), the focus remains on medical knowledge rather than patients' opinions and needs regarding quality of treatment and pain management.

Objectives: We aimed to identify what TMD patients want their dentists to know and do.

Methods: Open-ended questions were used to understand the perspectives of 6 TMD patients.

Neighborhood-Level Inequalities in Dental Care of Adolescents and Young Adults in Southwestern Ontario.

We examined whether the association of neighborhood-level socioeconomic status (SES) with the cost of dental care and dental care outcomes differs between adolescents and young adults. A total of 2915 patient records were split into two groups: adolescents (15 to 17 years of age) and young adults (18 to 24 years of age). Three dental care outcomes-routine oral evaluation (OEV-CH-A), utilization of preventive services (PRV-CH-A), and dental treatment services (TRT-CH-A)-were determined according to the Dental Quality Alliance (DQA) criteria.

Neighborhood Contexts and Oral Health Outcomes in a Pediatric Population: An Exploratory Study.

Aims: This study aimed to explore the impacts of neighborhood-level socioeconomic contexts on the therapeutic and preventative dental quality outcome of children under 16 years.

Materials And Methods: Anonymized billing data of 842 patients reporting to a university children's dental over three years (March 2017-2020) met the inclusion criteria. Their access to care (OEV-CH-A), topical fluoride application (TFL-CH-A) and dental treatment burden (TRT-CH-A) were determined by dental quality alliance (DQA) criteria.

Factors Influencing the Survival of Preformed Zirconia Crowns in Children Treated under General Anesthesia.

Aim: This study aimed to retrospectively evaluate the success of zirconia crowns placed in the anterior teeth of children and evaluate the impact of pulp therapy of the tooth on the rate of failure.

Materials And Methods: A total of 70 anterior teeth of 20 children aged between 3 and 5 years who had undergone the placement of zirconia crowns under general anesthesia were followed up for 24 months. Kaplan-Meier Survival curves were plotted for the estimation of two-year survival time.

The efficacy of two different oral hygiene regimens on the incidence and severity of oral mucositis in pediatric patients receiving hematopoietic stem cell transplantation: A prospective interventional study.

Aims: This prospective interventional study aimed to assess the efficacy of supersaturated calcium phosphate rinse and the use of an extra-soft toothbrush twice a day when added to the existing oral hygiene protocol regimen (0.12% chlorhexidine gluconate + 3% sodium bicarbonate + nystatin 5000 U/mL) in reducing the severity of oral mucositis among pediatric patients receiving chemotherapy for the hematopoietic stem cell transplant.

Methods: Forty-five patients that received chemotherapy for the hematopoietic stem cell transplant were randomly allocated to three groups of 15 patients each.

Color Stability of Glass Ionomer Cement after Reinforced with Two Different Nanoparticles.

Aim: This study aimed to compare the staining characteristics of a commercially available restorative glass ionomer cement to a formulation reinforced by the addition of carbon nanotubes and another formulation reinforced by the addition of silver nanoparticles to the powder of the same cement. . Twenty samples each of a control glass ionomer cement (PULPDENT® Glass Fill®, Pulpdent Corp.

Bite Force and Occlusal Patterns in the Mixed Dentition of Children with Down Syndrome.

Purpose: Oral function in Down Syndrome (DS) patients has been of interest to clinicians and researchers. This study aimed to evaluate the parameters of occlusal force and pattern of children with Down syndrome (DS) during mixed dentition when compared to age and gender-matched controls.

Materials And Methods: Thirty DS and 30 healthy children, aged 7 to 12 years, participated in the evaluation of the parameters of the occlusal pattern and occlusal force distribution analysis.

Impact of Presurgical Nasoalveolar Molding on the Parental Perceptions of Oral Health-related Quality of Life of Children with Cleft Lip and Palate.

Aim: The study aimed to examine the oral health-related quality of life (OHRQoL) of children with cleft lip and palate who were treated with presurgical nasoalveolar molding (PNAM) and to compare the results to age- and gender-matched controls without cleft lip and palate.

Materials And Methods: Parents of 51 children with cleft lip and palate who were treated with PNAM were administered a validated Arabic version of the short-form child oral health impact profile (COHIP-SF) and were asked to rate their experience with PNAM. The children with treated cleft lip and palate (study group) were age- and gender-matched to children with no cleft lip and palate (control group).

A Comparison of Salivary Mercury Levels in Children with Attention Deficit/Hyperactivity Disorder When Compared to Age-matched Controls: A Case-control Observational Study.

Aim: The aim of this study was to compare the level of mercury in the saliva of children with attention deficit/hyperactivity disorder (ADHD) as compared to age- and gender-matched controls in specific age groups.

Materials And Methods: A case-control observational study design was used. In school children with ADHD and outpatient dental clinics of a university dental hospital, the participants were schoolchildren diagnosed with ADHD studying in the first grade (6-7 years), sixth grade (12-13 years), and ninth grade (15-16 years) and were gender-matched to children without ADHD attending regular classes in school.

Relationship between type-I diabetes mellitus and oral health status and oral health-related quality of life among children of Saudi Arabia.

Introduction: The study was conducted to assess the impact of oral health status on the oral health-related quality of life (OHRQOL) of children between 12 and 15 years with type-1 diabetes mellitus (IDDM) in Saudi Arabia and compare these findings to age and gender matched medically fit children.

Materials And Method: A total of 40 children aged between 12 and 15 years with (IDDM) group presenting to the pediatric endocrinology clinic of the KSMC, Riyadh were age and gender matched to a control group of children reporting for a routine dental checkup at the dental clinics of the REU. The oral health of all children was recorded using WHO examination criteria.

A Comparison of Dental Caries in Urban and Rural Children of the Riyadh Region of Saudi Arabia.

The data presented in this study aimed to document caries prevalence and severity among a representative sample of 6, 12, and 15 years old Saudi Children. The study examined a total of 1,986 school children from 75 schools in urban and rural areas of Riyadh region, Saudi Arabia. Children having one or more dental caries lesion were used to determine prevalence of dental caries.

The Relationship between Salivary Total Antioxidant Capacity and Dental Caries in Children: A Meta-Analysis with Assessment of Moderators.

Objective: There has been variation reported in literature examining the relationship between dental caries and total antioxidant capacity (TAC) of saliva in children. This study aimed to systematically review the literature and conduct a meta-analysis of the association between dental caries and TAC in children.

Methodology: A systematic review of literature was done using the PubMed, Medline, and EBSCO libraries.

The Effects of Presurgical Nasoalveolar Molding on the Midface Symmetry of Children with Unilateral Cleft Lip and Palate: A Long-term Follow-up Study.

Background: Midface symmetry is an important indicator of success of complete unilateral cleft lip and palate (CUCLP) treatment. There is little literature on the long-term effects of presurgical nasoalveolar molding (PNAM) on midface symmetry in children treated for CUCLP. This study aimed to compare children with CUCLP who underwent PNAM before surgical interventions, children who did not receive PNAM, and age- and sex-matched controls in terms of midface symmetry.

Reliability of mobile phone teledentistry in dental diagnosis and treatment planning in mixed dentition.

Introduction: The aim of the study was to test the reliability of mobile phone teledentistry in the diagnosis and treatment planning of dental caries of children in mixed dentition.

Methods: A total of 57 cases, aged 6-12 years, among six examiners were used yielding 342 comparisons. The patients were examined by a dentist who was calibrated in the recording of oral findings in children using the World Health Organization (WHO) oral health assessment form for children (version 2013), which served as the gold standard for diagnosis.

Salivary antioxidant capacity of children with severe early childhood caries before and after complete dental rehabilitation.

Objective: There is a need to determine whether total antioxidant capacity (TAC) in severe early childhood caries (S-ECC) is an indicator of inflammatory response to the lesion or a marker of the disease. This study compared TAC levels in children with ECC before and after dental treatment and compared the results with those of caries-free children.

Design: Prospective study.

An Evaluation of Bite Pattern in Children with Severe-Early Childhood Caries Before and After Complete Dental Rehabilitation.

Purpose: The purpose of this study was to examine the changes in bite characteristics of children before and after the placement of multiple stainless steel crowns (SSCs) under general anesthesia (GA).

Methods: Twenty children scheduled for treatment under general anesthesia who needed SSCs in three or more posterior quadrants were included in this study. The bite was digitally analyzed and recorded preoperatively and at one and four weeks postoperatively.