Publications by authors named "Sharanya Kumar"
Article Synopsis
- Lymphangitic carcinomatosis (LC) is a serious condition often seen in advanced metastatic cancers, especially affecting the lungs, and presents symptoms like coughing and difficulty breathing.
- A 70-year-old man with generally good health experienced a persistent dry cough and other symptoms, leading to a diagnosis of Stage 4 prostate cancer with rare lung involvement.
- Imaging and biopsy confirmed the diagnosis, raising concerns for LC, which prompted urgent chemotherapy, highlighting the rarity of this condition in prostate cancer and its poor prognosis.
Over the years, several studies have revealed an important link between thyroid disorders and gallstone disease. According to these studies, hypothyroidism and hyperthyroidism are associated with cholesterol gallstone disease. This association between thyroid hormone disorders and cholesterol gallstone disease is due to the importance of thyroid hormones on cholesterol synthesis, bile functioning and content, and gallbladder motility.
View Article and Find Full Text PDFBackground: The impact of neurorehabilitation on patients with prolonged disorders of consciousness (PDOC) is not well known. We assessed the range of motion (ROM), muscle girth and power, level of consciousness, development of musculoskeletal deformity, and superficial sensation.
Methods: A retrospective observational record-based study was done, which included the data of patients diagnosed with PDOC admitted at Thumbay Physical Therapy & Rehabilitation Hospital, Ajman, UAE, between 2020 and 2022.
Background: Lung transplantation (LTx) has come as hope for select patients with post-COVID acute respiratory distress syndrome (ARDS). It has a different phenotype with unique challenges. We aimed to bring out our experience with and outcomes of LTx for post-COVID ARDS.
View Article and Find Full Text PDFBackground: Alzheimer's disease (AD) is the major cause of age-associated cognitive decline, and in the absence of effective therapeutics is progressive and ultimately fatal, creating a dire need for successful prevention and treatment strategies. We recently reported results of a successful proof-of-concept trial, using a personalized, precision medicine protocol, but whether such an approach is readily scalable is unknown.
Objective: In the case of AD, there is not a single therapeutic that exerts anything beyond a marginal, unsustained, symptomatic effect.
Background: Lung transplantation (LT) has emerged as a definitive cure for a plethora of end-stage lung diseases (ESLDs). With improvements in immune-suppression protocols, the posttransplantation survival rates have gone up.
Aim: The study reported the initial experience of the India's single largest lung transplant program on clinicopathological profile, procedures, challenges encountered, and outcomes.
Article Synopsis
- Migraine is a major global cause of disability, impacting work productivity and increasing healthcare expenses for those affected compared to the general population.
- The Migraine Impact Model (MIM) is a tool designed to help U.S. employers estimate the economic costs related to migraines among their employees, using input data like industry and employee demographics.
- Case studies show that MIM can project significant productivity losses, with millions of annual workdays affected and annual indirect costs being much greater than direct costs, aiding employers in making informed decisions to alleviate the migraine burden.
Growth modulation using functional appliances--cephalometric predictors of successful response.
Orthodontics (Chic.)
January 2014
Aim: The aim of this study was to determine any skeletal morphologic features evident on a pretreatment lateral cephalogram that may be used to predict improvement in the sagittal relationship during functional appliance therapy in Class II patients and compare changes between cases with and without a favorable response to growth modulation.
Method: Pretreatment and postfunctional lateral cephalograms were analyzed, and the change in the ANB angle was used to determine the skeletal response to treatment with a functional appliance. Based on the change in the ANB angle, the patients were divided into two groups of 12 patients each.
Background: Critical limb ischemia carries a significant risk of morbidity and mortality. The development of scores to predict risk can aid clinical decision making. The Bypass versus Angioplasty in Severe Ischaemia of the Leg (BASIL) trial investigators developed a model to predict death, which has not been previously validated.
View Article and Find Full Text PDFPurpose: To determine the role of peak systolic velocity (PSV) data provided by duplex ultrasound (DUS) surveillance in the prediction of endograft limb complications after endovascular aneurysm repair (EVAR).
Methods: All 478 consecutive patients (425 men; mean age 75±7 years) who underwent infrarenal EVAR between 2004 and 2010 had DUS scans at 1.5, 3, 6, 9, 12, and 18 months and annually thereafter over a median follow-up of 43 months (range 1-92).