Publications by authors named "Sharaf A"

Science is crucial for evidence-based decision-making. Public trust in scientists can help decision makers act on the basis of the best available evidence, especially during crises. However, in recent years the epistemic authority of science has been challenged, causing concerns about low public trust in scientists.

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Science is integral to society because it can inform individual, government, corporate, and civil society decision-making on issues such as public health, new technologies or climate change. Yet, public distrust and populist sentiment challenge the relationship between science and society. To help researchers analyse the science-society nexus across different geographical and cultural contexts, we undertook a cross-sectional population survey resulting in a dataset of 71,922 participants in 68 countries.

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"PolynetDWTCADx" is a sophisticated hybrid model that was developed to identify and distinguish colorectal cancer. In this study, the CKHK-22 dataset, comprising 24 classes, served as the introduction. The proposed method, which combines CNNs, DWTs, and SVMs, enhances the accuracy of feature extraction and classification.

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The exploration of perovskite compounds incorporating actinide and divalent elements reveals remarkable characteristics. Focusing on PbBkO, RaBkO, and SrBkO, these materials were studied using density functional theory (DFT) via the CASTEP code to analyze their electronic, optical, and mechanical properties. The results show semiconductor behavior, with respective band gaps of 1.

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A defect in the fusion of Müllerian ducts results in the uterine malformation of the bicornuate uterus. The bicornuate uterus is an uncommon condition, and it is associated with adverse early pregnancy and antenatal events, such as recurrent miscarriages, preterm labor, and delivery. The bicornuate uterus has two symmetric uterine cavities that are fused caudally and have some degree of communication between the two cavities, usually at the uterine isthmus.

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Background: Helicobacter pylori (H. pylori) infection increases the risks of chronic gastritis, peptic ulcer diseases, and the incidence of gastric cancer. However, antibiotic resistance and adverse effects led to the emergence of alternative treatments such as probiotics supplementation.

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Article Synopsis
  • The paper explores the use of Model-Free Predictive Control (MFPC) in power electronic systems, focusing on an improved adaptive integral sliding mode observer (AISMO) to better estimate unknown factors in an ultra-local model (ULM).
  • The proposed AISMO-MFPC aims to enhance control accuracy by estimating system parameters based on current errors, leading to independent control of the system.
  • To achieve lower current ripple, the method incorporates active vector execution time (AVET), allowing for multiple vector selections during a sampling period, which results in faster system responses and reduced harmonics.
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Coral reef ecosystems are under threat from climate change. Thus, active interventions to spur coral conservation/restoration are critical to support reef survival, greatly informed by a molecular understanding of resilience. The genus Acropora is a species-rich and globally prevalent reef builder that has experienced dramatic declines in the Caribbean.

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The effect of mechanical cues on cellular behaviour has been reported in multiple studies so far, and a specific aspect of interest is the role of mechanotransductive proteins in neuronal development. Among these, yes-associated protein (YAP) is responsible for multiple functions in neuronal development such as neuronal progenitor cells migration and differentiation while myocardin-related transcription factor A (MRTFA) facilitates neurite outgrowth and axonal pathfinding. Both proteins have indirectly intertwined fates via their signalling pathways.

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A wind turbine system (WTS) is a highly coupled and nonlinear system where the output power depends upon highly uncertain wind speed. Therefore, the quality of produced power becomes a challenging problem for researchers. Direct Vector Control (DVC) is a powerful and widely utilized power control strategy to deal with winds that vary rapidly and randomly.

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Twenty Crossbred (Baladi× Brown-Swiss) male growing-calves, 6 to 8 months old, weighing an average of 115 to 125 kg were subjected for evaluating ZADO supplementary effects on blood biochemical parameters, antioxidant status, thyroid activity, and growth efficiency of calves under semi-arid conditions. The experimental units were pinned equally in two groups. The control (G1) fed the basal ration, and the 2nd, treatment group (G2) fed the basal ration + a daily supplement of 10 g ZADO (exogenous enzymes) calf day in a powder form mixed well with ration.

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Article Synopsis
  • Methicillin-Resistant Staphylococcus aureus (MRSA) is a highly resistant bacteria causing various infections, and phages are seen as a promising alternative to antibiotics for treatment.
  • The study isolated a novel lytic phage, vB_SauP_ASUmrsa123, from sewage and clinical samples, confirming its effectiveness against MRSA using plaque assays and examining its morphology via electron microscopy.
  • Genome sequencing revealed that the phage has a linear dsDNA of approximately 17,155 bp with 24 predicted open reading frames (ORFs), suggesting its potential for targeting MRSA in infections.
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Objective: The United States has a lower life expectancy and wider income inequality than its similarly developed counterparts, and disparities continue to widen. The objective of our study is to examine the heterogeneity of disparities by income in cardiovascular disease (CVD) risk factors among U.S.

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Introduction Candida auris poses a significant healthcare challenge due to its high mortality rates, difficulties in identification, and resistance to antifungal treatment. This study aims to identify risk factors associated with 30-day mortality in patients with either invasive Candida auris infection or colonization. Methods We conducted a prospective study at Salmaniya Medical Complex, a tertiary care hospital in Bahrain, from September 2023 to February 2024.

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Introduction: The primary objective of this study is to report the results of an online questionnaire and the in-person discussion sessions of physicians specializing in diabetes care in which their opinions about current diabetes management was obtained.

Methods: The Diabetes Innovation Summit 2023 drew attendance from a diverse group of specialized physicians from multiple countries. A comprehensive literature review was conducted to examine the technologies and medical needs associated with diabetes management.

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Article Synopsis
  • In Jordan, traffic congestion and overcrowding in public hospitals hinder patients from timely collecting medications, a problem worsened by the COVID-19 pandemic; the Ministry of Health and Electronic Health Solutions are introducing a Medication Delivery System to address this issue.
  • The methodology proposed for this system includes a structured approach for developing requirements, integrating various health-related applications to ensure a comprehensive service, with extensive validation to meet stakeholder expectations.
  • The MDS was successfully implemented in a fraction of the anticipated time with no update requests post-implementation, highlighting the effectiveness of the requirements development process.
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Background: Hepatitis C virus (HCV) is a major risk factor for chronic hepatitis and hepatocellular carcinoma (HCC). Nuclear factor kappa B (NF-κB) is a transcription factor that functions in health and disease. Genetic variants of the NF-κB gene can affect its function and are associated with chronic inflammatory changes and malignant transformation.

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Article Synopsis
  • Alzheimer's disease (AD) causes significant cognitive decline and higher health risks in older adults, with mitochondrial dysfunction being a key contributor.
  • Mitochondrial issues include problems with energy metabolism, calcium regulation, and cellular damage, which are linked to several complex mechanisms in AD pathology.
  • While lecanemab is currently the only FDA-approved drug for AD, various therapies targeting mitochondrial dysfunction are explored, including antioxidants, nutritional supplements, and lifestyle changes like exercise.
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We previously published the microbial profile of burn wounds managed with NexoBrid® in Pinderfields Regional Burns Centre, Wakefield, UK. Our results showed no significant changes in bacterial colonisation in burn wounds debrided with NexoBrid®. Previous studies described the antimicrobial properties of bromelain enzyme.

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Background: The clinical presentations of coronavirus disease 2019 (COVID-19) exhibit significant variation, ranging from asymptomatic cases to mortality resulting from severe pneumonia. Host genetics can partially explain this variation.

Objective: This study evaluated possible associations between severity and outcome of COVID-19 and single nucleotide polymorphism (SNP) rs2285666 in the gene and SNP rs2070788 in the gene.

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Background: Prevention and treatment of the monkeypox virus (Mpox) remain challenging in areas where it is endemic. This systematic review and meta-analysis aimed to collect this information from various studies in one study to give a comprehensive view of people's opinions, fears, and behaviors about this virus.

Methods: We searched PubMed, Scopus, Web of Science, the Cochrane Library, and Google Scholar for descriptive cross-sectional study designs conducted in 2022 and 2023 addressing knowledge, attitude, perception, preparedness, willingness to get vaccinated, and practices against Mpox infection.

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Discharging patients directly to home from the intensive care unit (ICU) is becoming a new trend. This review examines the feasibility, benefits, challenges, and considerations of directly discharging ICU patients. By analyzing available evidence and healthcare professionals' experiences, the review explores the potential impacts on patient outcomes and healthcare systems.

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Conductive polymer nanocomposites for electromagnetic interference (EMI) shielding are important materials that can be combat the increasingly dangerous radiation pollution arising from electronic equipment and our surrounding environment. In this work, we have synthesized polyaniline-copper nanoparticles (PANI-Cu NPs) by the copper salt based oxidative polymerization method at room temperature and then added with different concentration (0, 1, 3 and 5 wt%) in polystyrene polymer forming PS/ PANI-Cu nanocomposites films by means of the traditional solution casting technique. The formed PANI-Cu NPs were investigated by UV/Vis spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM) and SEM/EDX elemental mapping techniques.

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The African BioGenome Project (AfricaBP) Open Institute for Genomics and Bioinformatics aims to overcome barriers to capacity building through its distributed African regional workshops and prioritizes the exchange of grassroots knowledge and innovation in biodiversity genomics and bioinformatics. In 2023, we implemented 28 workshops on biodiversity genomics and bioinformatics, covering 11 African countries across the 5 African geographical regions. These regional workshops trained 408 African scientists in hands-on molecular biology, genomics and bioinformatics techniques as well as the ethical, legal and social issues associated with acquiring genetic resources.

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Aim: Evaluate the effectiveness of biannual 38% SDF in arresting early childhood caries (ECC) compared to atraumatic restorative treatment (ART).

Methods: One hundred children (aged 2-5 years) with ECC were (2-5 years) divided equally and randomly into two groups. Test group: 38% SDF biannually; Control group: ART.

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