Publications by authors named "Shaposhnikov O"

The notion of a trophic ulcer is nosologically indefinite at present. Basing on current understanding of the pathogenesis of the processes that underlie the development of trophic ulcers on the lower limbs, the authors present a classification of such ulcers. They suggest a working scheme of trophic ulcers pathogenesis; according to this scheme, impaired blood microcirculation [correction of microhemocirculation] in the skin underlies the development of trophic ulcers on the lower limbs.

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Conservative treatment of trophic ulcers of the lower limbs should be combined, prolonged and continuous, universal and individualized with due consideration for the condition of the ulcer and the underlying process. Continuity of therapeutic measures carried out on an inpatient and outpatient basis is of great importance. Conservative treatment includes resting with the limb elevated, compensation of trophic ulcer activity symptoms, excess body mass control, prolonged intake of present-day angiotrophic drugs, courses of drug therapy to improve reparative processes, external therapy to improve trophic ulcer tissue condition.

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The authors' findings confirm the possibility of such forms. In 16.5% of cases lupus erythematosus transforms from the discoid form and in 6.

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A dynamic complex evaluation of immunologic vigor was carried out in 17 cases of Kaposi's sarcoma. Immunologic disorders were found to be in a correlation with clinical course. Three groups were identified: (1) patients with favourable prognosis (OKT4+/OKT8+ ratio--1.

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