Publications by authors named "Shapira Y"

Article Synopsis
  • This study explores the outcomes and management of pediatric auditory brainstem implantation (ABI) for children with severe inner ear malformations, aiming to unify clinical practices and address current challenges.
  • A systematic review of relevant findings from the Third International Pediatric ABI Symposium analyzed data from multiple countries, highlighting trends in auditory outcomes, surgical approaches, and rehabilitation strategies.
  • Key conclusions emphasize the need for standardized guidelines and improved collaboration among healthcare professionals to enhance patient outcomes and guide future research in this specialized field.
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  • The study aimed to assess the effectiveness of subconjunctival tranexamic acid (TXA) in reducing bleeding, shortening surgery time, and enhancing recovery in pterygium surgery through a double-blind, randomized controlled trial involving 50 patients.
  • Results showed no significant differences between the TXA group and the saline control group in terms of surgery duration, intraoperative bleeding, or postoperative visual acuity, with both groups faring similarly in all main outcome measures.
  • Although the use of TXA was deemed safe with no adverse effects, the findings suggest that it does not provide substantial benefits in improving surgical outcomes for pterygium surgery, indicating a need for further research on alternative treatments or surgical techniques.
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Article Synopsis
  • Conjunctival melanoma, a rare type of ocular melanoma, has some genetic similarities to both skin and mucosal melanoma and presents unique treatment challenges when advanced or metastatic.
  • The FDA recently approved the combination treatment Nivolumab/relatlimab (Opdualag) for metastatic melanoma, showing improved survival rates in earlier treatment stages without significant safety concerns, but its effectiveness in conjunctival melanoma is still unknown.
  • In a case study, an 87-year-old woman with advanced conjunctival melanoma showed a near-complete clinical response after just one cycle of Opdualag, although treatment was limited to four cycles due to her worsening dementia.
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Background: Foreign bodies that migrate into the heart may include medical devices dislodged from their original location or, rarely, external particles (shrapnel and other foreign bodies) that penetrate the vein, remain intraluminal, and migrate via the venous blood flow to the right heart. Most reported entry sites of these external foreign bodies were in the torso, thigh, or neck; none of them penetrated through a distal extremity of the body. We report a case where shrapnel was found in the right ventricle (RV) following penetrating injury to the hand.

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Despite diagnostic and therapeutic advances, infective endocarditis (IE) is still associated with high mortality rates. Currently, there are no good prognostic tools for the risk assessment of patients with IE. The CHADS-VASc score, used to estimate the risk of ischemic stroke in patients with non-valvular atrial fibrillation (AF), has been shown to be a powerful predictor of stroke and death in patients without known AF associated with other cardiovascular conditions.

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Purpose: Automatic speech analysis (ASA) and automatic speech recognition systems are increasingly being used in the treatment of speech sound disorders (SSDs). When utilized as a home practice tool or in the absence of the clinician, the ASA system has the potential to facilitate treatment gains. However, the feedback accuracy of such systems varies, a factor that may impact these gains.

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Objective: Common peroneal (fibular) neuropathy is the most common mononeuropathy of the lower extremity. Despite this, there are surprisingly few studies on the topic, and a knowledge gap remains in the literature. As one attempts to address this knowledge gap, a core outcome set (COS) is needed to guide the planning phases of future studies to allow synthesis and comparability of these studies.

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The Mpemba effect is a counterintuitive phenomena in which a hot system reaches a cold temperature faster than a colder system, under otherwise identical conditions. Here, we propose a quantum analog of the Mpemba effect, on the simplest quantum system, a qubit. Specifically, we show it exhibits an inverse effect, in which a cold qubit reaches a hot temperature faster than a hot qubit.

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This study investigates the morphological changes in grape pips resulting from various charring conditions. Employing high-resolution scanning combined with morphometric measurements for morphological analysis, we aimed to understand the effects of charring on grape pips. Our morphometric analysis demonstrated significant alterations in seed shape above 250 °C.

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Background: Transcranial ultrasound stimulation (TUS) is a non-invasive brain stimulation technique; when skull aberrations are compensated for, this technique allows, with millimetric accuracy, circumvention of the invasive surgical procedure associated with deep brain stimulation (DBS) and the limited spatial specificity of transcranial magnetic stimulation.

Objective: /hypothesis: We hypothesize that MR-guided low-power TUS can induce a sustained decrease of tremor power in patients suffering from medically refractive essential tremor.

Methods: The dominant hand only was targeted, and two anatomical sites were sonicated in this exploratory study: the ventral intermediate nucleus of the thalamus (VIM) and the dentato-rubro-thalamic tract (DRT).

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Objective: Describe the clinical profile of revision cochlear implantation (RCI) cases involving device manufacturer conversion (RCI), compare them to cases without manufacturer conversion (RCI), and classify the reasons for manufacturer conversion (MC).

Study Design: Retrospective case review.

Setting: Tertiary academic center.

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Background: To determine the quality and reliability of DCR YouTube videos as patient education resources and identify any associated factors predictive of video quality.

Methods: A YouTube search was conducted using the terms "Dacryocystorhinostomy, DCR, surgery" on 12th of January 2022, with the first 50 relevant videos selected for inclusion. For each video, the following was collected: video hyperlink, title, total views, months since the video was posted, video length, total likes/dislikes, authorship (i.

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Rationale & Objective: Kidney function can be adversely affected by significant tricuspid regurgitation (TR) owing to effects on cardiac output and systemic venous congestion. However, the impact of significant TR on short- and long-term kidney function following a kidney transplant remains uncertain.

Study Design: Retrospective observational cohort.

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: The aim of this study is to report outcomes of eyelid full-thickness skin grafting augmentation in facial nerve palsy (FNP) patients younger than 50 years of age. : In a retrospective, consecutive case series, nine eyelid skin grafts performed on eight FNP patients with skin contraction (five females; median age 42 years [range, 17-47]) are presented. In most cases, upper eyelid skin grafting was combined with levator recession and anterior lamellar repositioning.

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Article Synopsis
  • End-stage renal disease significantly increases cardiovascular risks, but kidney transplantation can help reduce these risks, even in patients with systolic heart failure.
  • A study of 604 kidney transplant patients revealed that 28% experienced a notable improvement in heart function post-transplant, with female patients showing greater recovery.
  • The findings suggest that kidney transplantation can improve left ventricular systolic function in certain patients, highlighting its potential benefits even for those with heart issues.
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Objective: When considering traumatic brachial plexus and upper extremity nerve injuries, iatrogenic nerve injuries, and nontraumatic nerve injuries, brachial plexus and upper extremity nerve injuries are commonly encountered in clinical practice. Despite this, data synthesis and comparison of available studies are difficult. This is at least in part due to the lack of standardization in reporting and a lack of a core outcome set (COS).

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: Since its invention in the 1970s, the cochlear implant (CI) has been substantially developed. We aimed to assess the trends in the published literature to characterize CI. : We queried PubMed for all CI-related entries published during 1970-2022.

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We propose a method to extract the mutual exchange statistics of the anyonic excitations of a general Abelian fractional quantum Hall state, by comparing the tunneling characteristics of a quantum point contact in two different experimental conditions. In the first, the tunneling current between two edges at different chemical potentials is measured. In the second, one of these edges is strongly diluted by an earlier point contact.

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Introduction: Transcranial focused ultrasound therapy (tcFUS) offers precise thermal ablation for treating Parkinson's disease and essential tremor. However, the manual fine-tuning of fiber tracking and segmentation required for accurate treatment planning is time-consuming and demands expert knowledge of complex neuroimaging tools. This raises the question of whether a fully automated pipeline is feasible or if manual intervention remains necessary.

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The present study aimed to examine whether individual differences in baseline speech perception could serve as predictors for the effectiveness and generalization of auditory training (AT) to non-trained tasks. Twelve adults, aged 60-75 years with bilateral hearing loss, completed a two-month, home-based, computerized AT program, involving sessions four times per week. Training tasks included the identification of vowel frontal, height, manner of articulation, point of articulation, voicing, and open-set consonant-vowel-consonant (CVC) words.

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Article Synopsis
  • Ulnar neuropathy at the elbow (UNE) affects a notable portion of the population, but there is no clear agreement on treatment methods due to inconsistent outcome reporting in studies.
  • This study aimed to create a Core Outcome Set for UNE (COS-UNE) using the modified Delphi method, involving stages like literature review and consensus surveys.
  • The final COS-UNE includes 22 key outcomes spanning various domains, establishes guidelines for reporting, and stresses the importance of consistent data collection in future research on UNE.
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Little is known about the natural history of non-significant mitral and tricuspid regurgitation (MR and TR) following surgical aortic valve replacement (SAVR) for aortic regurgitation (AR). We retrospectively analyzed 184 patients (median age 64 (IQR, 55-74) years, 76.6% males) who underwent SAVR for AR.

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Unlabelled: - Objective: To explore the clinical validity of elastic deformation of optical coherence tomography (OCT) images for data augmentation in the development of deep-learning model for detection of diabetic macular edema (DME).

Methods: Prospective evaluation of OCT images of DME (n = 320) subject to elastic transformation, with the deformation intensity represented by ([Formula: see text]). Three sets of images, each comprising 100 pairs of scans (100 original & 100 modified), were grouped according to the range of ([Formula: see text]), including low-, medium- and high-degree of augmentation; ([Formula: see text] = 1-6), ([Formula: see text] = 7-12), and ([Formula: see text] = 13-18), respectively.

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Background: Intracapsular resection of head and neck peripheral nerve sheath tumors (PNST) has emerged as a nerve-preserving technique compared to en bloc resection. The aim of this study was to evaluate and compare the functional outcome of both surgical techniques performed at a single tertiary referral center.

Methods: This is a retrospective cohort of patients with head and neck PNST undergoing surgical resection from 2011 to 2021 at the Tel Aviv Sourasky Medical Center.

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Objective: To evaluate dynamic magnetic resonance dacryocystography (MRDCG) in eyes with functional epiphora.

Methods: We included prospective eyes with epiphora if no alternative cause was found on clinical examination, were patent on syringing, had no obstruction or stenosis on DCG, and had an abnormal DSG. MRDCG was performed to qualitatively assess for block or patency and quantitatively measure tear transit time.

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