Regional BDE-209 emission, environmental fate and risks: Methods establishment, data filling and feature analysis.

BDE-209 is an emerging environmental contaminant that poses a significant threat to human health. Despite its inclusion in the Stockholm Convention, the current regional emission levels, environmental fate, and corresponding risks remain unclear, especially with the ongoing release of BDE-209 during the disposal of waste electrical and electronic equipment. The significant gaps in BDE-209 emission data highlight the need for a regional approach to better understand these issues.

Degradation and detoxification of 6PPD-quinone in water by ultraviolet-activated peroxymonosulfate: Mechanisms, byproducts, and impact on sediment microbial community.

N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q) has been identified to induce acute toxicity to multifarious aquatic organisms at exceptionally low concentrations. The ubiquity and harmful effects of 6PPD-Q emphasize the critical need for its degradation from water ecosystems. Herein, we explored the transformation of 6PPD-Q by an ultraviolet-activated peroxymonosulfate (UV/PMS) system, focusing on mechanism, products and toxicity variation.

Biodegradation pathway and mechanism of tri (2-chloropropyl) phosphate by Providencia rettgeri.

Tri (2-chloropropyl) phosphate (TCPP) was an emerging contaminant of global concern because of its frequent occurrence, potential toxic effects, and persistence in the environment. Microbial degradation might be an efficient and safe removal method, but limited information was available. In this study, Providencia rettgeri was isolated from contaminated sediment and showed it could use TCPP as unique phosphorus source to promote growth, and decompose 34.

The combined toxicity of polystyrene nano/micro-plastics and triphenyl phosphate (TPHP) on HepG2 cells.

Combined toxicity is a critical concern during the risk assessment of environmental pollutants. Due to the characteristics of strong hydrophobicity and large specific surface area, microplastics (MPs) and nanoplastics (NPs) have become potential carriers of organic pollutants that may pose a health risk to humans. The co-occurrence of organic pollutants and MPs would cause adverse effects on aquatic organism, while the information about combined toxicity induced by organophosphorus flame retardants and MPs on human cells was limited.

Evaluation of pharmaceutical consumption between urban and suburban catchments in China by wastewater-based epidemiology.

Wastewater-based epidemiology (WBE) is amply used for estimating human consumption of chemicals, yet information on regional variation of pharmaceuticals and their environmental fate are scarce. Thus, this study aims to estimate the consumption of three cardiovascular, four non-steroidal anti-inflammatory pharmaceuticals (NSAIDs), and four psychoactive pharmaceuticals between urban and suburban catchments in China by WBE, and to explore their removal efficiencies and ecological risks. Eleven analytes were detected in both influent and effluent samples.

Exploring the molecular mechanism of Chlorella vulgaris in response to androstenedione exposure based on genes continuously up-regulated in transcription analysis.

Androstenedione (ADSD) is one of the widely detected androgens in diverse aquatic environments. However, there were few reports on the molecular mechanism of Chlorella vulgaris exposure to ADSD. In our previous research, we have investigated the genes associated with chlorophyll metabolism in Chlorella vulgaris response to ADSD.

Granulocyte Colony-Stimulating Factor Improves Endothelial Progenitor Cell-Mediated Neovascularization in Mice with Chronic Kidney Disease.

Patients with chronic kidney disease (CKD) have a higher prevalence of peripheral arterial disease (PAD), and endothelial progenitor cells (EPCs) play a pivotal role. We examined the impact of granulocyte colony-stimulating factor (G-CSF) on EPC function in response to tissue ischemia. Eight-week-old male C57BL/6J male mice were divided into sham operation and subtotal nephrectomy (SNx) groups, received hindlimb ischemic operation after seven weeks, then randomly received G-CSF or PBS intervention for four weeks with weekly follow-ups.

Insights into electrochemical oxidation of tris(2-butoxyethyl) phosphate (TBOEP) in aquatic media: Degradation performance, mechanisms and toxicity changes of intermediate products.

Tris (2-butoxyethyl) phosphate (TBOEP) has gained significant attention due to its widespread presence and potential toxicity in the environment. In this study, the degradation of TBOEP in aquatic media was investigated using electrochemical oxidation technology. The anode Ti/SnO-Sb/La-PbO demonstrated effective degradation performance, with a reaction constant (k) of 0.

Using artificial intelligence algorithms to predict the overall survival of hemodialysis patients during the COVID-19 pandemic: A prospective cohort study.

Background: Hemodialysis (HD) patients are a vulnerable population at high risk for severe complications from COVID-19. The impact of partial COVID-19 vaccination on the survival of HD patients remains uncertain. This prospective cohort study was designed to use artificial intelligence algorithms to predict the survival impact of partial COVID-19 vaccination in HD patients.

Metagenomic insights into the mechanisms of triphenyl phosphate degradation by bioaugmentation with Sphingopyxis sp. GY.

Biodegradation of triphenyl phosphate (TPHP) by Sphingopyxis sp. GY was investigated, and results demonstrated that TPHP could be completely degraded in 36 h with intracellular enzymes playing a leading role. This study, for the first time, systematically explores the effects of the typical brominated flame retardants, organophosphorus flame retardants, and heavy metals on TPHP degradation.

Assessments of the effects of tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on human intestinal health from the aspects of intestinal flora changes and cytotoxicity to human cells.

Organophosphorus flame retardants (OPFRs) are now drawing the public's attention due to their potential toxicity. Given that contaminated food may result in the ingestion of OPFRs to the human intestine, further investigation is required to determine the potential adverse effects of these compounds on human intestinal health. The present study aimed to comprehensively assess the effect of tris(1,3-dichloro-2-propyl) phosphate (TDCPP), a typical OPFR, on human intestinal health by evaluating both intestinal flora and human cell Caco-2.

Dermoscopic Image Classification Method Using an Ensemble of Fine-Tuned Convolutional Neural Networks.

Aiming at the problems of large intra-class differences, small inter-class differences, low contrast, and small and unbalanced datasets in dermoscopic images, this paper proposes a dermoscopic image classification method based on an ensemble of fine-tuned convolutional neural networks. By reconstructing the fully connected layers of the three pretrained models of Xception, ResNet50, and Vgg-16 and then performing transfer learning and fine-tuning the three pretrained models with the ISIC 2016 Challenge official skin dataset, we integrated the outputs of the three base models using a weighted fusion ensemble strategy in order to obtain a final prediction result able to distinguish whether a dermoscopic image indicates malignancy. The experimental results show that the accuracy of the ensemble model is 86.

Urinary concentrations of bisphenol analogues in the south of China population and their contribution to the per capital mass loads in wastewater.

Bisphenol analogues (BPs) are heavily used and negatively affect the health of human beings, however, there is little knowledge regarding human exposure to BPs other than BPA. This study aims to assess human exposure to BPs through investigating pooled urine and wastewater samples. Twenty-four pooled urine samples were prepared from 960 specimens (classified by age and gender).

Simultaneous adsorption of Cd and photocatalytic degradation of tris-(2-chloroisopropyl) phosphate (TCPP) by mesoporous TiO.

In this work, the prepared mesoporous TiO was employed to eliminate the environmental risk induced by the combined pollution (tris-(2-chloroisopropyl) phosphate (TCPP) and Cd). The prepared material was characterized by X-ray diffraction (XRD), UV-vis diffuse reflectance spectra (UV-DRS), Raman imaging spectrometer (Raman), N adsorption/desorption isotherm and X-ray photoelectron spectroscopy (XPS). In the combined pollution system, the prepared TiO simultaneously exhibited a higher adsorption and photocatalytic activity for Cd and TCPP at neutral condition, respectively.

Transcriptome profiling of Pseudomonas aeruginosa YH reveals mechanisms of 2, 2', 4, 4'-tetrabrominated diphenyl ether tolerance and biotransformation.

Aerobic degradation of 2, 2', 4, 4'-tetrabrominated diphenyl ether (BDE-47) by Pseudomonas aeruginosa YH (P. aeruginosa YH) were investigated in this study. BDE-47 degradation was mainly through the biological action of intracellular enzymes, and the metabolites included debrominated metabolites (BDE-28 and BDE-7), hydroxylated metabolites (6-OH-BDE-47, 5-OH-BDE-47, 2'-OH-BDE-28 and 4'-OH-BDE-17), and brominated phenols (2,4-DBP and 4-BP).

In vitro biotransformation and evaluation of potential transformation products of chlorinated paraffins by high resolution accurate mass spectrometry.

Chlorinated paraffins (CPs) are high production chemicals, which leads to their ubiquitous presence in the environment. To date, few studies have measured CPs in humans and typically at relatively low concentrations, despite indications that exposure may be high compared to various persistent organic pollutants. The aim of this study is to investigate the in vitro biotransformation of CPs by human liver fractions.

Insights into the electrochemical degradation of triclosan from human urine: Kinetics, mechanism and toxicity.

Electrochemical degradation of triclosan in human urine was firstly studied by using Ti/SnO-Sb/PbO anode doped with rare-earth elements. The results indicated that the Ti/SnO-Sb/Gd-PbO anode demonstrated the best performance with the degradation rate constants being 0.095 min in fresh urine and 0.

Urinary Concentrations of Bisphenols in the Australian Population and Their Association with the Per Capita Mass Loads in Wastewater.

Health concerns and related regulation of bisphenol A (BPA) in some countries have led to an increase in the production and use of unregulated and poorly understood BPA analogues, including bisphenol S (BPS), bisphenol F (BPF), bisphenol B (BPB), and bisphenol AF (BPAF). To assess the temporal trends of human exposure to BPA analogues, urine and wastewater samples were collected from South East Queensland, Australia between 2012 and 2017 and analyzed for five bisphenols using validated isotope dilution liquid chromatography tandem mass spectrometry methods. BPA and BPS were the predominant bisphenols detected in both urine and wastewater samples, with median concentrations of 2.

Removal of sulfamethazine and Cu by Sakaguchia cladiensis A5: Performance and transcriptome analysis.

To reduce the potential risks of contamination of antibiotics and heavy metals to ecological environment and human safety, biological removal of these composite pollutants is the focus of much study. One previously identified isolate, Sakaguchia cladiensis A5, was used to decompose sulfamethazine (SMZ) and adsorb Cu. The ability of A5 to remove SMZ was enhanced by pre-induced culture, which reached 49.

Concentrations of phthalate metabolites in Australian urine samples and their contribution to the per capita loads in wastewater.

Exposure to phthalates is a public health concern. In this study, we collected both urine and wastewater samples from 2012 to 2017 and analysed for 14 phthalate metabolites to assess human exposure to phthalates in Southeast Queensland (SEQ), and for associations between phthalate metabolites in urine and wastewater samples. Twenty-four pooled urine samples were prepared from 2400 individual specimens every two years (stratified by age, gender and collection year).

Insights into the degradation and detoxication mechanisms of aqueous capecitabine in electrochemical oxidation process.

Electrocatalytic oxidation and detoxication of capecitabine (CAP) in aqueous solution were investigated with Ti/SnO-Sb/Ce-PbO anode. The relative contributions of generated free radicals showed an increase in the pseudo zero order tare constants in the following order: OH (9.4%) < SO (24.

Effects of benzo [a] pyrene (BaP) on the composting and microbial community of sewage sludge.

Benzo [a] pyrene (BaP), the most ubiquitous polycyclic aromatic hydrocarbons (PAHs) found in sludge, can impact the composting processes of sewage sludge as well as the quality of compost produced. In the present study, we investigated the effects of BaP at various concentrations on physicochemical characteristics, heavy metal passivation, and microbial community during the composting processes. The removal efficiency of BaP at 5 and 20 mg kg after composting was 51.

Concentrations of Organophosphate Esters and Their Specific Metabolites in Food in Southeast Queensland, Australia: Is Dietary Exposure an Important Pathway of Organophosphate Esters and Their Metabolites?

There were several studies that measured organophosphate esters (OPEs) in foods to assess the dietary intake of OPEs but none has measured OPE metabolites (mOPEs) in the same samples. In this study, we measured the concentrations of OPEs and mOPEs in 87 food samples and in five tap water samples collected in Queensland, Australia belonging to eight food groups. Tris(2-chloroisopropyl) phosphate (TCIPP) (detection frequency (DF), 77%) and tributyl phosphate (TBP) (DF, 71%), were the most frequently detected OPEs, while dibutyl phosphate (DBP) (DF, 84%) and diphenyl phosphate (DPhP) (DF, 86%) were the most frequently detected mOPEs.

[Effects of Exogenous Microorganism Inoculation on Efficiency and Bacterial Community Structure of Sludge Composting].

In this study, municipal sludge, sawdust, and mushroom residues were used as raw materials for composting, and thermophiles and white-rot fungi were added into the compost in stages. By measuring physicochemical factors, including temperature, pH value, organic matter, water-soluble organic carbon, moisture content, total nitrogen, NH-N, NO-N, and germination index during the composting process, the effect of exogenous bacteria inoculation on the efficiency of compost was determined. By means of high-throughput sequencing technology, the variation of bacterial community structure and the impact of exogenous bacteria inoculation on bacterial community structure during sludge composting were also investigated.