The Framework of Quantifying Biomarkers of OCT and OCTA Images in Retinal Diseases.

Despite the significant advancements facilitated by previous research in introducing a plethora of retinal biomarkers, there is a lack of research addressing the clinical need for quantifying different biomarkers and prioritizing their importance for guiding clinical decision making in the context of retinal diseases. To address this issue, our study introduces a novel framework for quantifying biomarkers derived from optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images in retinal diseases. We extract 452 feature parameters from five feature types, including local binary patterns (LBP) features of OCT and OCTA, capillary and large vessel features, and the foveal avascular zone (FAZ) feature.

Heart failure classifications via non-invasive pressure volume loops from echocardiography.

Background: Left ventricular pressure-volume (LV-PV) loops provide comprehensive characterization of cardiovascular system in both health and disease, which are the essential element of the hemodynamic evaluation of heart failure (HF). This study attempts to achieve more detailed HF classifications by non-invasive LV-PV loops from echocardiography and analyzes contribution of parameters to HF classifications.

Methods: Firstly, non-invasive PV loops are established by time-varying elastance model where LV volume curves were extracted from apical-four-chambers view of echocardiographic videos.

Vessel Segmentation of X-Ray Coronary Angiographic Image Sequence.

Objective: To facilitate the analysis and diagnosis of X-ray coronary angiography in interventional surgery, it is necessary to extract vessel from X-ray coronary angiography. However, vessel images of angiography suffer from low quality with large artefacts, which challenges the existing vascular technology.

Methods: In this paper, we propose a ávessel framework to detect vessels and segment vessels in angiographic vessel data.

Robust phase unwrapping for phase images in Fourier domain Doppler optical coherence tomography.

To solve the 2 ? phase ambiguity for phase-resolved Doppler images in Doppler optical coherence tomography, we present a modified network programming technique for the first time to the best of our knowledge. The proposed method assumes that error of the discrete derivatives between unwrapped phase image and wrapped phase image can be arbitrary values instead of integer-multiple of 2 ? , which makes the real-phase restoration accurate and robust against noise. We compared our proposed method with the network programming method.

Adaptive anisotropic diffusion for noise reduction of phase images in Fourier domain Doppler optical coherence tomography.

Phase image in Fourier domain Doppler optical coherence tomography offers additional flow information of investigated samples, which provides valuable evidence towards accurate medical diagnosis. High quality phase images are thus desirable. We propose a noise reduction method for phase images by combining a synthetic noise estimation criteria based on local noise estimator (LNE) and distance median value (DMV) with anisotropic diffusion model.