Microglial DBP Signaling Mediates Behavioral Abnormality Induced by Chronic Periodontitis in Mice.

Several lines of evidence implicate that chronic periodontitis (CP) increases the risk of mental illnesses, such as anxiety and depression, yet, the associated molecular mechanism for this remains poorly defined. Here, it is reported that mice subjected to CP exhibited depression-like behaviors and hippocampal memory deficits, accompanied by synapse loss and neurogenesis impairment in the hippocampus. RNA microarray analysis disclosed that albumin D-site-binding protein (DBP) is identified as the most prominently upregulated target gene following CP, and in vivo and in vitro immunofluorescence methods showed that DBP is preferentially expressed in microglia but not neurons or astrocytes in the hippocampus.

[Application of modified Frosch approach for Schatzker typeⅡtibial plateau fractures with posterolateral column].

Objective: To explore clnical efficacy of modified Frosch approach for Schatzker typeⅡtibial plateau fracture with posterolateral column.

Methods: From January 2019 to September 2020, totally 11 patients with Schatzker typeⅡtibial plateau fractures with posterolateral column were treated, including 7 males and 4 females, aged from 21 to 49 years old. Modified Frosch approach was adopted for lateral decubitus position, and posterolateral fractures were fixed with support plates or posterolateral screws.

The Synthesis of Amino-Acid-Anchored Two-Dimensional Silicoaluminophosphates and Congo Red Adsorption Application.

Two-dimensional (2D) materials with nanometer thickness have the advantage of a large specific surface area and excellent surface accessibility. They have great potential for adsorption, catalysis, and many other applications. 2D zeolitic silicoaluminophosphates (SAPOs) can be synthesized through a dual structure directing agent (SDA) strategy.

Relationship between leaf vein traits of three dominant species and ecological factors in the Qinling Mountains, China.

We investigated the inter- and intra-species differences of leaf vein traits of three dominant species, , var. , and of Niubeiling (subtropical humid climate) and Taohuagou (warm temperate semi-humid climate), located in the eastern and western Qinling Mountains. The nine examined leaf vein traits included primary leaf vein width, secondary leaf vein width, mean fine vein width, primary vein density, fine vein density, vein areole diameter, areole density, 3D fine vein surface area, and fine vein volume.

The Mediating Role of Attitudes Towards Dementia on the Relationship Between Dementia Knowledge and Behaviors Towards Persons with Dementia: A Cross-Sectional Study.

Purpose: To examine the mediating effect of attitudes towards dementia on the relationship between dementia knowledge and behaviors towards persons with dementia.

Participants And Methods: A cross-sectional survey was conducted with 313 adults (age ≤ 20 years). Participants were recruited using non-probability convenience sampling from medical clinics, community centers, and supermarkets located in the Wanhua District of Taipei City.

Construction of Low-Coordination Cu-C Single-Atoms Electrocatalyst Facilitating the Efficient Electrochemical CO Reduction to Methane.

Constructing Cu single-atoms (SAs) catalysts is considered as one of the most effective strategies to enhance the performance of electrochemical reduction of CO (e-CO RR) towards CH , however there are challenges with activity, selectivity, and a cumbersome fabrication process. Herein, by virtue of the meta-position structure of alkynyl in 1,3,5-triethynylbenzene and the interaction between Cu and -C≡C-, a Cu SAs electrocatalyst (Cu-SAs/HGDY), containing low-coordination Cu-C active sites, was synthesized through a simple and efficient one-step method. Notably, this represents the first achievement of preparing Cu SAs catalysts with Cu-C coordination structure, which exhibited high CO -to-CH selectivity (72.

Comparison of species composition and community characteristics of forests on south and north slopes of Taibai Mountain, China.

We examined species composition, community characteristics, diversity, and community similarity of five communities composed of three species (, var, ) on the altitudinal gradient on the south and north slopes of Taibai Mountain. The results showed that there was an altitudinal transition pattern from pure forest to . variabilis- var mixed forest, var pure forest, var mixed forest and pure forest on the south and north slopes of Taibai Mountain.

New Insight into the Electronic Effect for Cu Porphyrin Catalysts in Electrocatalytic of CO into CH.

Perturbation of the copper (Cu) active site by electron manipulation is a crucial factor in determining the activity and selectivity of electrochemical carbon dioxide (CO ) reduction reaction (e-CO RR) in Cu-based molecular catalysts. However, much ambiguity is present concerning their electronic structure-function relationships. Here, three molecular Cu-based porphyrin catalysts with different electron densities at the Cu active site, Cu tetrakis(4-methoxyphenyl)porphyrin (Cu─T(OMe)PP), Cu tetraphenylporphyrin (Cu─THPP), and Cu tetrakis(4-bromophenyl)porphyrin (Cu─TBrPP), are prepared.

Construction of Synergistic Ni S -MoS Nanoheterojunctions on Ni Foam as Bifunctional Electrocatalyst for Hydrogen Evolution Integrated with Biomass Valorization.

The intrinsic sluggish kinetics of the oxygen evolution reaction (OER) limit the improvement of hydrogen evolution reaction (HER) performance, and substituting the anodic oxidation of biomass materials is an alternative approach, given its lower oxidation potential and higher added value compared to those of OER. In this study, a Ni S -MoS nanoheterojunction catalyst with strong electronic interactions is prepared. It exhibits high efficiency for both the HER and the electrooxidation of 5-hydroxymethylfurfural (HMF).

High-Performance Zeolitic Hollow-Fiber Membranes by a Viscosity-Confined Dry Gel Conversion Process for Gas Separation.

Zeolite membranes show great potential for gas and hydrocarbon separations, but high manufacturing cost has been one of the main hurdles in their industrial application. Here we demonstrate a method termed viscosity-confined dry gel conversion (VCDGC) for zeolite hollow fiber membrane fabrication. We demonstrate in detail the VCDGC synthesis of small-pore CHA zeolite membranes.

The Impact of Global Budgeting on the Efficiency of Healthcare under a Single-Payer System in Taiwan.

Since 1995, a national health insurance (NHI) program has been in operation in Taiwan, which provides uniform comprehensive coverage. Forced by severe financial deficit, global budgeting reimbursement was adopted in the healthcare sector to control healthcare expenditures in 2002. A two-stage data envelopment analysis (DEA) approach was used to measure the efficiency of hospital resource allocation among stakeholders in Taiwan's NHI system, and to further explore the changes in resource allocation after the introduction of a global budgeting payment scheme.

Muscle Mass and Gait Characteristics in Older Women Fallers vs. Non-Fallers.

Background: Falling is a major public health concern of elderly people. We aimed to determine if lean mass and spatiotemporal gait parameters could predict the risk of falling in elderly women and also study the relationships between lean mass and gait characteristics.

Methods: Twenty-four community women were prospectively recruited (mean age, 72.

Cu-doped cerium oxide-based nanomedicine for tumor microenvironment-stimulative chemo-chemodynamic therapy with minimal side effects.

CeO nanoenzyme possesses multiple enzyme-mimicking activities and excellent biocompatibility. However, its weak peroxidase (POD)-mimicking property in the tumor microenvironment (TME) hinders its further tumor therapy application. To enhance CeO nanoenzyme's POD activity and overcome limitations of single therapeutic modality, a novel antitumor controlled drug release system (CCCs NPs) was designed using Cu doped cerium oxide nanoparticles (Cu-CeO NPs) loaded with clinical anti-cancer drug doxorubicin (DOX) as the core and the breast cancer cell membrane as the outer shell.

Determining the stability of minimally displaced lateral humeral condyle fractures in children: ultrasound is better than arthrography.

Background: Evaluating of the articular cartilage status of the distal humeral epiphysis is difficult. Ultrasound imaging of the elbow is increasingly being used to confirm the integrity of the articular cartilage of minimally displaced lateral humeral condyle fractures in children with minimally displaced fractures. The aims of this study were to assess the correlations between ultrasound and arthrography findings for predicting the integrity of the cartilage hinge and to describe the utility of ultrasound in determining the need for pre-treatment.

Entropy-Based Effect Evaluation of Delineators in Tunnels on Drivers' Gaze Behavior.

Driving safety in tunnels has always been an issue of great concern. Establishing delineators to improve drivers' instantaneous cognition of the surrounding environment in tunnels can effectively enhance driver safety. Through a simulation study, this paper explored how delineators affect drivers' gaze behavior (including fixation and scanpath) in tunnels.

All-Nanoporous Hybrid Membranes: Incorporating Zeolite Nanoparticles and Nanosheets with Zeolitic Imidazolate Framework Matrices.

Metal-organic framework (MOF) membranes have attractive molecular separation properties but require challenging thin-film deposition techniques on expensive/specialty supports to obtain high performance relative to conventional polymer membranes. We demonstrate and analyze in detail the new concept of all-nanoporous hybrid membranes (ANHMs), which combines two or more nanoporous materials of different morphologies into a single membrane without the use of any polymeric materials. This allows access to a previously inaccessible region of very high permeability and selectivity properties, a feature that enables ANHMs to show high performance even when fabricated with simple coating and solvent evaporation methods on low-cost supports.

Detecting normal pediatric brain development with diffusional kurtosis imaging.

Purpose: To characterise the pattern of change of diffusional kurtosis imaging (DKI) parameters (including kurtosis and diffusion parameters) in both white matter and gray matter in normal brain development with a large sample of subjects from term-born neonates to 14-years old children.

Methods: Two hundred and eighteen normal children (136 male, 82 female) underwent conventional magnetic resonance imaging and DKI. Regions of interest (ROIs) were placed in 7 white matter areas and 4 gray matter areas.

Hyperspectral indirect inversion of heavy-metal copper in reclaimed soil of iron ore area.

To explore a rapid detection technology for detecting heavy metals in soil based on hyperspectral data, this paper took an iron mine in Daye Country, Hubei Province, as the research area, used a FieldSpec4 portable ground object spectrometer to obtain soil spectral reflectance and combine the measured data, and used three spectral transformation methods: first-order differential, second-order differential, and continuum removal. We studied the indirect hyperspectral inversion of heavy metals in reclaimed soils in the iron mine area by using three models: partial least squares regression, support vector machine, and back propagation (BP) neural network. The results show that spectral transformation can effectively highlight the position of spectral characteristic bands and improve the correlation between spectral curves and iron (Fe) element concentration.

Evaluating the sustainable traffic flow operational features of an exclusive spur dike U-turn lane design.

The traditional U-turn design has significantly improved traffic operations for relieving traffic congestion. However, the U-turn diversion and merge segments still cause traffic conflicts and delays. In this paper, an exclusive spur dike U-turn lane (ESUL) is proposed with the aim of addressing the disadvantages of the traditional U-turn design.

Continuous Zeolite MFI Membranes Fabricated from 2D MFI Nanosheets on Ceramic Hollow Fibers.

High-quality 2D MFI nanosheet coatings were prepared on α-alumina hollow fiber supports by vacuum filtration and then transformed into molecular sieving membranes by two sequential hydrothermal treatments. This processing method eliminates the need for specially engineered silica-based support materials that have so far been necessary to allow the formation of functional membranes from 2D MFI nanosheets. The sequential steps enhance adhesion of the membrane on the fiber support, fill in nanoscale gaps between the 2D nanosheets, and preserve the desirable (0k0) out-of-plane orientation without the need of any support engineering or modification.

Lumbar muscle volume in postmenopausal women with osteoporotic compression fractures: quantitative measurement using MRI.

Objective: To investigate the relationship between paraspinal and psoas muscle volumes and acute osteoporotic or low-bone-mass compression fractures of the lumbar spine in postmenopausal women.

Methods: Patient data were retrieved retrospectively for postmenopausal women with L-spine magnetic resonance imaging (MRI) and dual-energy X-ray absorptiometry showing osteoporosis/low bone mass. Group 1 comprised eight women aged 60-80 years with MRI showing a single acute compression fracture.

Ultrathin ZSM-5 zeolite nanosheet laminated membrane for high-flux desalination of concentrated brines.

The tremendous potential of zeolite membranes for efficient molecular separation via size-exclusion effects is highly desired by the energy and chemical industries, but its practical realization has been hindered by nonselective permeation through intercrystalline spaces and high resistance to intracrystalline diffusion in the conventional zeolite membranes of randomly oriented polycrystalline structures. Here, we report the synthesis of ZSM-5 zeolite nanosheets with very large aspect ratios and nanometer-scale thickness in the preferred straight channel direction. We used these ZSM-5 nanosheets to fabricate ultrathin (<500 nm) laminated membranes on macroporous alumina substrates by a simple dip-coating process and subsequent consolidation via vapor-phase crystallization.

Ion-Exchanged SAPO-34 Membranes for Krypton-Xenon Separation: Control of Permeation Properties and Fabrication of Hollow Fiber Membranes.

Separation of radioisotope Kr from Xe is of importance in used nuclear fuel reprocessing. Membrane separation based on zeolite molecular sieves such as chabazite SAPO-34 is an attractive alternative to energy-intensive cryogenic distillation. We report the synthesis of SAPO-34 membranes with considerably enhanced performance via thickness reduction based upon control of a steam-assisted vapor-solid conversion technique followed by ion exchange with alkali metal cations.