Publications by authors named "Shaosen Li"

The growing activity of hemangioma of spleen keeps unknown. To search theoretical basis for whether to take the operation, this study analyzed clinical data of 21 hemangioma patients, and 16 surgical specimens were analyzed immunohistochemistry of Ki-67, Bcl-2 and vascular endothelial growth factor (VEGF). Both 14 cases of cavernous hemangioma were positive for VEGF, and negative in capillary hemangioma, there was statistical significant difference between two types of hemangioma (P < 0.

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Purpose: There are no global screening recommendations for esophageal squamous cell carcinoma (ESCC). Endoscopic screening has been investigated in areas of high incidence in China since the 1970s. This study aimed to evaluate whether an endoscopic screening and intervention program could reduce mortality caused by ESCC.

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Esophageal cancer is the 6th most common cancer in the world, and genetic factors (p53 mutations) in addition to the environmental factors (food, nutrition, smoking, drinking, etc.) are involved in its development. In this study, the association between the both factors, environmental risk factors for esophageal cancer and p53 mutations, in tumor tissues was investigated in 77 patients living in a high-incidence area and 50 patients living in a low-incidence area in Hebei Province, China.

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Aim: To define the age scope of high-risk population for esophageal cancer (EC) in Ci county.

Methods: The results of endoscopic examination of 2 013 subjects, cytological screening of 16 763 persons and records of 9 265 patients with EC were analyzed by Ridit methods, the standard age group was 45-49 year group.

Results: The average age of patients with moderate esophageal epithelium dysplasia by endoscopic examination was 53.

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Article Synopsis
  • The study focused on mutations in the p53 tumor-suppressor gene, commonly found in esophageal cancer, analyzing samples from 207 patients in China.
  • Researchers compared two detection methods: single-strand conformation polymorphism (SSCP) and denaturing high-performance liquid chromatography (DHPLC), finding DHPLC had better sensitivity (97%) than SSCP (81%) for identifying mutations.
  • Results indicated that DHPLC detected a higher number of mutations (49%) compared to SSCP (41%), and it was particularly effective at identifying smaller mutations that SSCP missed.
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Aim: To characterize the histological types of esophageal and cardiac mucosa by endoscopic survey of a population in a high-risk area of esophageal cancer of China.

Methods: A selected cohort of residents in Cixian County during December 2001 and May 2002 was surveyed by using Lugol's staining, followed by computer-based statistical analysis of the data with SPSS 10.0 software.

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Aim: To describe the incidence of esophageal cancer (EC) in Cixian, a county of Hebei province during 1974-1996. We analyzed the sex and age characteristics as well as the geographic distribution of EC, in order to determine the impact so that methods of preventing and controlling EC in Cixian can be put in place.

Methods: Since the early 1970s, the cancer registry system has been established, which collects the cancer incidence in Cixian county.

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