Metabolomic profiling of ocular tissues in rabbit myopia: Uncovering differential metabolites and pathways.

To investigate the metabolic difference among tissue layers of the rabbits' eye during the development of myopia using metabolomic techniques and explore any metabolic links or cascades within the ocular wall. Ultra Performance Liquid Chromatography - Mass Spectrometry (UPLC-MS) was utilized for untargeted metabolite screening (UMS) to identify the significant differential metabolites produced between myopia (MY) and control (CT) (horizontal). Subsequently, we compared those key metabolites among tissues (Sclera, Choroid, Retina) of MY for distribution and variation (longitudinal).

Central toxic keratopathy after small incision lenticule extraction surgery:A case report.

Purpose: To report a rare case of central toxic keratopathy after small incision lenticule extraction surgery (SMILE).

Case Report: A 38-year-old female presented with visual loss 10 days after undergoing SMILE. Subsequently, transparent band keratopathy was protruded in the left cornea and corneal cap opacity was increased, which was accompanied by hyperopic shift and corneal thinning.

Effects of Corneal Stromal Lens Collagen Cross-Linking Regraft on Corneal Biomechanics.

Background: Corneal collagen cross-linking (CXL) therapy, a method that uses a combination of riboflavin and ultraviolet-A light (UVA), can promote the formation of covalent cross-linking of amino acid residues of corneal collagen and enhance the hardness of the cornea. In this study, we explored the effects of corneal stromal lens collagen cross-linking regraft on corneal biomechanics.

Methods: A total of 15 New Zealand white rabbits were divided into 3 groups: normal control group (group A), SMILE + uncross-linked lens implantation group (Group B), and SMILE + cross-linking lens implantation group (group C).

Effects of V4c-ICL Implantation on Myopic Patients' Vision-Related Daily Activities.

The new type implantable Collamer lens with a central hole (V4c-ICL) is widely used to treat myopia. However, halos occur in some patients after surgery. The aim is to evaluate the effect of V4c-ICL implantation on vision-related daily activities.

Four-year follow-up of corneal aberrations and visual functions of myopic patients after laser in situ keratomileusis.

Objective: To report on 4-year follow-up of corneal higher-order aberrations and daily visual functions of myopic patients after laser in situ keratomileusis (LASIK).

Methods: One hundred thirty four eyes of 67 patients who underwent LASIK guided by aspherical ablation were included in this study. The vision, corneal spherical aberration (SphA) and Coma were recorded before LASIK and at 6 month and 4 year after LASIK.