Research on the acoustic emission characteristics and instability correlation effect of the dynamic response of waste dump slopes.

Due to the fluidity of the loose medium inside the waste dump slope, the traditional monitoring system cannot fully reflect the misalignment and slip between particles inside the medium, and it is also difficult to capture the precursor information of the slip of the loose accumulation body. To reveal the dynamic evolution process of the slope instability of the waste dump slope, the coupling test system of the slope instability of the waste dump slope was used to carry out the study of the acoustic emission characteristics of the slope instability dynamic response of the dump slope under the action of vibration, and to quantitatively analyse the staged characteristics of the acoustic emission parameter evolution of the dump slope under the action of different vibration frequencies and its instability initiation node. The results show that with the increase of vibration frequency, the damage mode of the slope model gradually changes from sliding of small particles to large-scale landslides, and presents the stage process of "vibration compaction → vibration equilibrium → dynamic instability"; Under the action of low-frequency and high-amplitude, the slope model mainly shows that the tiny particles and the basement gravel slip, which is difficult to capture with the naked eye, while under the action of high-frequency and low-amplitude, the slope surface is damaged in a large area, and the overall model is unstable; The dynamic instability of the waste dump slope is accompanied by obvious acoustic emission activities, and the changes of the characteristic parameters of acoustic emission reveal, to a certain extent, the evolution of the internal state of the slope in the process of dynamic instability of the waste dump slope and its stage characteristics; The amplitude and energy efficiency of acoustic emission in the time domain show obvious fractal characteristics in the dynamic instability of the waste dump slope.

Who Can Help Me? Citizens' Help-Seeking on Weibo During the Shanghai Lockdown.

Objective: In the context of the Omicron-induced lockdown in Shanghai, this paper investigated the appeals for assistance by citizens on Weibo, aiming to understand their principal challenges and immediate needs.

Methods: This paper collected Weibo posts ( 1040) containing the keyword "Shanghai Anti-epidemic Help" during the citywide lockdown. The online help requests from Shanghai citizens were analyzed across 7 dimensions, including the help sought, level of urgency, help recipient, the intended beneficiary of the help, expression, position, and emotion.

Application of machine learning for the differentiation of thymomas and thymic cysts using deep transfer learning: A multi-center comparison of diagnostic performance based on different dimensional models.

Objective: This study aimed to evaluate the feasibility and performance of deep transfer learning (DTL) networks with different types and dimensions in differentiating thymomas from thymic cysts in a retrospective cohort.

Materials And Methods: Based on chest-enhanced computed tomography (CT), the region of interest was delineated, and the maximum cross section of the lesion was selected as the input image. Five convolutional neural networks (CNNs) and Vision Transformer (ViT) were used to construct a 2D DTL model.

Relationship between starch fine structure and simulated oral processing of cooked rice.

Background: Simulated oral processing can be used to evaluate the palatability of cooked rice. Previously, we established a simulated oral processing method using a texture analyzer equipped with a multiple extrusion cell probe (TA/MEC). However, the relationship between oral processing and starch fine structure remains unknown.

Subaxial lordosis loss and influence factors after posterior atlantoaxial fusion.

Unlabelled: Cervical sagittal balance is an important evaluation index of cervical physiological function and surgical efficacy. Subaxial kyphosis after atlantoaxial fusion is negatively associated with worse clinical outcomes and higher incidence of lower cervical disk degeneration.

Objectives: This study aimed to confirm the factors that influence subaxial lordosis loss after posterior atlantoaxial fusion.

A novel variant in fibrillin-1 is responsible for early-onset familial thoracic aortic aneurysms in Marfan patients.

Background: Marfan syndrome (MFS) is an inherited connective tissue disorder that affects the skeletal, ocular, and cardiovascular system. The disease's severity and clinical manifestations vary greatly due to pathogenic variants which, combined with a lack of research on the correlation between MFS's genotype and phenotype, make MFS a challenging disease to diagnose. This study aims to further the understanding of MFS by shedding light on the clinical manifestation of a novel variant in fibrillin-1 ()-the protein responsible for the genetic defects that lead to MFS.

Evaluation of Percutaneous Transforaminal Endoscopic Discectomy in the Treatment of Lumbar Disc Herniation: A Retrospective Study.

Objective: The objective of the present study was to evaluate the safety and efficacy of percutaneous transforaminal endoscopic discectomy (PTED) and open fenestration discectomy (OFD) in the treatment of lumbar disc herniation (LDH).

Methods: Patients in our hospital with LDH who received PTED (n = 71) and OFD (n = 39) from 2013 to 2014 were retrospectively studied. Patient information, including age, gender, visual analogue scale (VAS) score for low back pain and leg pain, body weight, height, Oswestry disability index (ODI), Japanese Orthopedic Association (JOA), and recurrence, was collected.

A novel missense mutation of RPGR identified from retinitis pigmentosa affects splicing of the ORF15 region and causes loss of transcript heterogeneity.

Mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene, are the major cause of X-linked retinitis pigmentosa (RP), in which exon open reading frame 15 (ORF15) of RPGR has been implicated to play a substantial role. We identified a novel hemizygous missense mutation E585K of RPGR from whole-exome sequencing of RP. RNA-Seq analysis and functional study were conducted to investigate the underlying pathogenic mechanism of the mutation.

A combined ultrasonic B-mode and color Doppler system for the classification of breast masses using neural network.

Objectives: To develop a dual-modal neural network model to characterize ultrasound (US) images of breast masses.

Materials And Methods: A combined US B-mode and color Doppler neural network model was developed to classify US images of the breast. Three datasets with breast masses were originally detected and interpreted by 20 experienced radiologists according to Breast Imaging-Reporting and Data System (BI-RADS) lexicon ((1) training set, 103212 masses from 45,433 + 12,519 patients.

Polymicrobial and Monomicrobial Infections after Spinal Surgery: A Retrospective Study to Determine which Infection is more Severe.

Study Design: A retrospective clinical review.

Purpose: To investigate the difference in clinical manifestations and severity between polymicrobial and monomicrobial infections after spinal surgery.

Overview Of Literature: Surgical site infections (SSIs) after spinal surgery are a major diagnostic and therapeutic challenge for spinal surgeons.

[Clinical value of 64-slice spiral 3-phase CT enhanced scanning for preoperative TNM staging assessment of gastric carcinoma].

Objective: To explore the clinical value of 64-slice spiral 3-phase CT enhanced scanning for preoperative TNM staging assessment of gastric carcinoma.

Methods: A retrospective study was performed to review the 64-slice spiral 3-phase CT enhanced scanning of 120 patients with gastric cancer diagnosed by biopsy prior to operation and postoperative pathological reports. All the findings were reviewed by two senior radiologic diagnosticians separately and compared with pathological findings.

Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes.

Refractory wounds in diabetic patients constitute a serious complication that often leads to amputation with limited treatment regimens. The present study was designed to determine the protective effect of the soy isoflavone genistein on diabetic wound healing and investigate underlying mechanisms. Streptozotocin (STZ)-induced type 1 diabetic mice with full-thickness excisional wounds received 0.

[Research advances on aquaporins and vascular function regulation and related diseases].

Aquaporins (AQPs), mainly distributed in epithelial and endothelial cells, are a family of channel-forming membrane proteins, originally confirmed to mediate the cellular water-transportation. AQPs are essential for maintaining homeostasis of the body water. Recently, studies have shown that AQPs may be involved in vascular function regulation and the development of related diseases, especially in cerebral ischemia, congestion heart failure, hypertension and tumor angiogenesis.

Ganoderma lucidum polysaccharide accelerates refractory wound healing by inhibition of mitochondrial oxidative stress in type 1 diabetes.

Background/aims: Refractory wounds in diabetic patients constitute a serious complication that often leads to amputation with limited treatment regimens. The present study was designed to determine the protective effect of Ganoderma lucidum polysaccharide (Gl-PS) on diabetic wound healing and investigate underlying mechanisms.

Methods: Streptozotocin (STZ)-induced type 1 diabetic mice with full-thickness excisional wounds were intragastrically administered with 10, 50 or 250 mg/kg/day of Gl-PS.