Existing research on the post-heating processing of fermented milk has primarily focused on single post-heating treatments and the texture, while research on how changes in metabolites during different post-heating treatments affect flavor and sensory properties is limited. This study investigates the changes in volatile metabolites in fermented milk treated at different post-heating temperatures to determine the characteristic aroma types and analyzes the changes in non-volatile metabolites associated with aroma-active compounds or their precursors to clarify the causes of the altered flavor and sensory properties. The results showed that in the 65 °C and 75 °C treatments, 63 volatile compounds were produced by Strecker degradation, lipid oxidation and esterification to produce ketones and aldehydes.
View Article and Find Full Text PDFChieh-qua is an important cucurbit crop and very popular in South China and Southeast Asia. Despite its significance, its genetic basis and domestication history are unclear. In this study, we have successfully generated a chromosome-level reference genome assembly for the chieh-qua 'A36' using a hybrid assembly strategy that combines PacBio long reads and Illumina short reads.
View Article and Find Full Text PDFsubsp. YLGB-1496 (YLGB-1496) is a probiotic strain isolated from human breast milk. The application of YLGB-1496 is influenced by carbohydrate utilization and genetic stability.
View Article and Find Full Text PDFJ Obstet Gynaecol Res
July 2024
Setting: Previous studies addressed the association between anti-thyroid antibodies and recurrent miscarriage (RM), however, the role of anti-thyroid antibodies in RM patients is debatable.
Objectives: Therefore, we conducted this meta-analysis and the aim of this current study was to assess whether anti-thyroid peroxidase (anti-TPO) and/or anti-thyroglobulin (anti-TG) antibody positivity was associated with RM.
Design: A meta-analysis was conducted.
Background: The use of synbiotics is emerging as a promising intervention strategy for regulating the gut microbiota and for preventing or reducing obesity, in comparison with the use of probiotics or prebiotics alone. A previous in vivo study revealed that Lacticaseibacillus paracasei K56 (L. paracasei K56) could alleviate obesity induced in high-fat-diet mice; however, the effect of the synbiotic combination of L.
View Article and Find Full Text PDFBackground: The basic leucine zipper (bZIP) transcription factor family is one of the most abundant and evolutionarily conserved gene families in plants. It assumes crucial functions in the life cycle of plants, including pathogen defense, secondary metabolism, stress response, seed maturation, and flower development. Although the genome of wax gourd has been published, little is known about the functions, evolutionary background, and gene expression patterns of the bZIP gene family, which limits its utilization.
View Article and Find Full Text PDFLigustilide (LIG) is the main active ingredient of Angelica sinensis (Oliv.) Diels, which could promote focal angiogenesis to exert neuroprotection. However, there was no report that verified the exact effects of LIG on endometrial angiogenesis and the pregnancy outcomes.
View Article and Find Full Text PDFBackground: Women with antiphospholipid syndrome (APS) or antiphospholipid antibodies (aPLs) are at high risk for obstetric complications, including recurrent pregnancy loss (RPL). However, effective treatments for RPL are lacking.
Objective: This study aimed to reveal the function and underlying mechanism of hyperoside (Hyp) in RPL associated with antiphospholipid antibodies (aCLs).
Probiotics could improve cognitive functions in patients with neurological disorders such as Alzheimer’s disease, but the effects on cognitive function in healthy older adults without cognitive impairment need further study. The purpose of this study was to investigate the effect of Bifidobacterium longum BB68S (BB68S) on cognitive functions among healthy older adults without cognitive impairment. A randomized, double-blind, placebo-controlled trial was conducted with 60 healthy older adults without cognitive impairment who were divided into probiotic or placebo groups and required to consume either a sachet of probiotic (BB68S, 5 × 1010 CFU/sachet) or placebo once daily for 8 weeks.
View Article and Find Full Text PDFis used extensively in the fermented milk-beverage industry as a starter culture. Acid production capacity during fermentation is the main criterion for evaluating starters although it is strain-dependent. In this study, the acid production rates of 114 strains were determined and then classified into high acid (HC), medium acid (MC), and low acid (LC) groups.
View Article and Find Full Text PDFAnticardiolipin antibody (aCL), an important characterization of antiphospholipid syndrome, shows an intense association with vascular endothelial injury. Hyperoside is a flavonoid extracted from medicinal plants traditionally used in Chinese medicines, displaying anti-inflammatory, anti-cancer, and anti-oxidative properties in various diseases. Recent studies have shifted the focus on the protective effects of hyperoside on vascular endothelial injury.
View Article and Find Full Text PDFChaihu-Shugan-San (CSS), a classic Chinese formula, has long been used to treat depression. For a better and rational use of this formula, here, we investigated the comprehensive pharmacokinetic features of multiple ingredients from CSS using ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry (UPLC-QTOF-MS) in depressed rats. Force swimming experiments were conducted to establish a rat model of depression.
View Article and Find Full Text PDFBackground: Currently, few herbal pharmacokinetic (PK) parameters have been applied successfully for therapeutic monitoring because of the complexity of consistency when there are multiple chemicals and efficacies.
Purpose: The present study aims to evaluate the herbal PK properties by investigating the PK parameters of the 8 absorbed bioactive compounds (ABCs), which can represent its parent herbal holistic efficacy, to achieve a PK therapeutic monitoring of herbs.
Method: First, we tested the hypothesis that the antidepressant and prokinetic effects and related anti-inflammation and anti-oxidation activity (APIO) by Fructus aurantii-Magnolia Bark (FM) formula are related to 8 compounds according to the absorbable evidence and the determined contents.
1. The pharmacokinetics (PKs) analysis of compounds absorbed after the oral administration of Si-Ni-San (SNS) decoction to functional dyspepsia (FD) patients was designed to detect whether the effects were similar to prokinetics administered to healthy rats, without ethical limitation. 2.
View Article and Find Full Text PDFEcotoxicol Environ Saf
February 2006
The anaerobic biodegradability of 23 nitrogenous compounds, including nitrogenous heterocyclic compounds and aliphatic amines, was tested and assessed in integration. These nitrogenous compounds were classified into readily, partially, and poorly biodegradable compounds after calculation of their integrated assessment indices (IAIs), Rules for anaerobic biodegradation of these compounds were also drawn. Stepwise regression and backpropagation artificial neural network (BP-ANN) methods were applied to establish quantitative structure-biodegradability relationships (QSBRs) based on the assessment results.
View Article and Find Full Text PDFSci Total Environ
April 2006
Anaerobic biodegradability of 46 kinds of aromatic compounds was tested and assessed in integrate. These aromatic compounds were classified into readily, partially and poorly biodegradable compounds after their integrated assessment indices (IAI) were calculated. Some rules of anaerobic biodegradation of them were drawn.
View Article and Find Full Text PDFAnaerobic biodegradability of organic compounds can be assessed from the changes in organic compounds, the end products, and the activity of microorganisms. In this study, all three of these variables were considered to integrate assessment of the anaerobic biodegradability of organic compounds. The analytical hierarchy process (AHP) was introduced to integrate the assessment.
View Article and Find Full Text PDFIn this study, anaerobic biodegradability of 47 kinds of aliphatic compounds was tested and assessed in integrate. These aliphatic compounds were classified into readily, partially and poorly biodegradable compounds after their integrated assessment indices (IAI) were calculated. Some laws of anaerobic biodegradation of aliphatic compounds were drawn.
View Article and Find Full Text PDFEcotoxicol Environ Saf
November 2002
This study assessed anaerobic biodegradability of organic compounds from microorganism activity. Dehydrogenase activity can be a good parameter characterizing the microorganism activity. A modified method of 2-(p-iodophenyl-3-(p-nitrophenyl)-5-pheny tetrazolium chloride-dehydrogenase activity determination was proposed in anaerobic biodegradability assessment.
View Article and Find Full Text PDFThere are various kinds of trace ions in water supply, such as Na+, K+, Ca2+, Mg2+ and Cl-, SO(4)2-, CO(3)2- etc. 17O-NMR chemical shift and line-width of water were measured under different temperature and different concentrations of various salts in aqueous solutions containing those ions. The relationship of 17O-NMR chemical shift and line-width of water to water association and the effect of ions on water association were analyzed.
View Article and Find Full Text PDFIn this paper, the amount of oxygen consumption, end products and activities of microorganisms are considered as the three factors which affect the biodegradability of organic substances in water. Two integrated assessment methods for biodegradability of organic substances, fuzzy clustering integrated assessment and weighted integrated assessment, have been developed. Simultaneously, the detail steps for assessing a new organic substance biodegradability with these two integrated assessment methods are proposed.
View Article and Find Full Text PDF