Functionalized amino acid-based injectable hydrogels for sustained drug delivery.

Drug delivery vehicles optimize therapeutic outcomes by enhancing drug efficacy, minimizing side effects, and providing controlled release. Injectable hydrogels supersede conventional ones in the field of drug delivery owing to their less invasive administration and improved targeting. However, they face challenges such as low biodegradability and biocompatibility, potentially compromising their effectiveness.

Chemical modification of β-cyclodextrin towards hydrogel formation.

β-CD is a cyclic oligosaccharide, which has trunked cone like structure. The unique structure makes it efficient for numerous applications. Though, the native β-CD has many issues like low solubility, absence of sufficient functionalities and lower complexation ability with guest molecules.