A systematic review and meta-analysis on the effectiveness of bivalent mRNA booster vaccines against Omicron variants.

Background: A global shift to bivalent mRNA vaccines is ongoing to counterbalance the diminishing effectiveness of the original monovalent vaccines due to the evolution of SARS-CoV-2 variants, yet substantial variation in the bivalent vaccine effectiveness (VE) exists across studies and a complete picture is lacking.

Methods: We searched papers evaluating absolute or relative effectiveness of SARS-CoV-2 BA.1 type or BA.

A Wireless Visualized Sensing System with Prosthesis Pose Reconstruction for Total Knee Arthroplasty.

The surgery quality of the total knee arthroplasty (TKA) depends on how accurate the knee prosthesis is implanted. The knee prosthesis is composed of the femoral component, the plastic spacer and the tibia component. The instant and kinetic relative pose of the knee prosthesis is one key aspect for the surgery quality evaluation.