Publications by authors named "Shaojun Gu"
Article Synopsis
- Scientists created a tool called U-AKIpredTM to help doctors predict if critically ill patients will get acute kidney injury (AKI) within 12 hours, using urine tests.
- They studied 680 patients, and found that 12 specific markers in urine, especially three main ones, were great for this prediction.
- The tool showed really good results, helping doctors make decisions to prevent or treat AKI more effectively, and it can be accessed online for easy use.
The paper summarizes the interactions between luteolin (glucosides) and drug-metabolizing enzyme from the literature of recent years and our research work. The metabolism of luteolin is chiefly mediated by phase II metabolic enzyme. Its glucosides are firstly hydrolyzed into aglycone in intestinal tract, and then absorbed and metabolized.
View Article and Find Full Text PDF[Metabolism-based interaction of diphenytriazol and flavone compounds].
Zhejiang Da Xue Xue Bao Yi Xue Ban
March 2008
Objective: To observe the metabolism-based interaction of diphenytriazol and flavone compounds.
Methods: Flavone compounds kaempferol, isoharmnten and Elsholtzia blanda benth extract were chosen as the substrate of glucuronidation in the phase II metabolism. The metabolism was investigated in different rat liver microsome incubates pretreated with beta-naphthoflavone (BNF), diphenytriazol and tea oil (control).