Knockdown the moyamoya disease susceptibility gene, RNF213, upregulates the expression of basic fibroblast growth factor and matrix metalloproteinase-9 in bone marrow derived mesenchymal stem cells.

Moyamoya disease (MMD) is a chronic, progressive cerebrovascular occlusive disease. Ring finger protein 213 (RNF213) is a susceptibility gene of MMD. Previous studies have shown that the expression levels of angiogenic factors increase in MMD patients, but the relationship between the susceptibility gene RNF213 and these angiogenic mediators is still unclear.

Lattice Incorporation of Cu into the BaCeZrYYbO Electrolyte on Boosting Its Sintering and Proton-Conducting Abilities for Reversible Solid Oxide Cells.

Lattice modification by incorporating heteroatoms could effectively and precisely tune their intrinsic properties to get improved sinterability and electrochemical performance. Here, by introducing Cu into the interstitial position of a ABO-type perovskite, a 2 times higher protonic conductivity (1.9 × 10 S cm at 700 °C) and low-temperature (1200 °C) sinterability were achieved for the BaCeZrYYbCuO (BCZYYC2) electrolyte, compared to the precursor electrolyte.