Porous Organic Polymer Supported Nano Ruthenium Catalysts for Cascade Aromatization of Quinoxalin-2(1)-one and C-H Annulation with Alkynes.

Selective C-H annulation with alkynes is one of the most useful tools to synthesize heterocycles. Herein, we developed novel porous organic polymers supported ruthenium (POPs-Ru) as highly efficient catalysts for cascade aromatization of quinoxalin-2(1)-one and C-H annulation with alkynes. Both terminal and internal alkynes were successfully transferred to furo[2,3]quinoxaline derivatives with good functional group tolerance and high regioselectivity by using POPs-Ru catalysts.

Ruthenium-Catalyzed Dehydrogenative Intermolecular O-H/Si-H/C-H Silylation: Synthesis of ()-Alkenyl Silyl-Ether and Silyl-Ether Heterocycle.

Selective dehydrogenative silylation is one of the most valuable tools for synthesizing organosilicon compounds. In this study, a regio- and stereoselective ruthenium-catalyzed dehydrogenative intermolecular silylation was firstly developed to access ()-alkenyl silyl-ether derivatives and silyl-ether heterocycles with good functional group tolerance. Furthermore, two pathways for RuH(CO)(PPh)/NBE-catalyzed dehydrogenative intermolecular silylation of alcohols and alkenes as well as intermolecular silylation of naphthol derivatives were investigated with HSiEt as the hydrosilane reagent.

Visible light-induced cascade -alkylation/amidation reaction of quinazolin-4(3)-ones and related N-heterocycles.

An efficient and visible light-promoted cascade -alkylation/amidation of quinazolin-4(3)-ones with benzyl halides and allyl halides has been described for the first time to provide a convenient access to quinazoline-2,4(1,3)-diones. This cascade -alkylation/amidation reaction shows good functional group tolerance and could also be applied to N-heterocycles such as benzo[]thiazoles, benzo[]imidazoles, and quinazolines. Control experiments show that KCO plays an important role in this transformation.