Simultaneous Detection of Biomarkers in Urine Using a Multicalibration Potentiometric Sensing Array Combined with a Portable Analyzer.

Domestic monitoring devices make real-time and long-term health monitoring possible, allowing people to track their health status regularly. Uric acid (UA), creatinine, and urea in urine are three important biomarkers for various diseases, especially kidney diseases. This work proposed a 10-channel potentiometric sensing array containing a UA electrode group, a creatinine electrode group, a urea electrode group, a pH electrode group, and one pair of reference channels, which could be connected with a portable potentiometric analyzer, realizing the simultaneous detection of UA, creatinine, urea, and pH in urine.

Revealing the adulteration of sesame oil products by portable Raman spectrometer and 1D CNN vector regression: A comparative study with chemometrics and colorimetry.

Identification and quantification of sesame oil products are crucial due to the existing problems of adulteration with lower-priced oils and false labeling of sesame proportions. In this study, 1D CNN models were established to achieve discrimination of oil types and multiple quantification of adulteration using portable Raman spectrometer. An improved data augmentation method involving discarding transformations that alter peak positions was proposed, and synchronously injecting noise during geometric transformations.

Identification of antibiotic residues in aquatic products with surface-enhanced Raman scattering powered by 1-D convolutional neural networks.

Universal and fast antibiotic residues detection technology is imperative for the control of food safety in aquatic products. However, accurate surface-enhanced Raman scattering (SERS) quantitative detection of complicated samples is still a challenge. A recognition method powered by deep learning and took advantage of the unique fingerprint information merits of SERS was proposed.

A bioinspired porous-designed hydrogel@polyurethane sponge piezoresistive sensor for human-machine interfacing.

Conductive coating sponge piezoresistive pressure sensors are attracting much attention because of their simple production and convenient signal acquisition. However, manufacturing sponge-structure pressure-sensing materials with high compressibility and wide pressure detection ranges is difficult because of the instability of rigid and brittle conductive coatings at large strains. Herein, a tough conductive hydrogel@polyurethane (PU) sponge with a porous design is prepared immersion of a polyurethane sponge in a low-cost and biocompatible polyvinyl alcohol (PVA)/glycerin (Gl)/sodium chloride (NaCl) solution.

Poly(vinyl alcohol)/phosphoric acid gel electrolyte@polydimethylsiloxane sponge for piezoresistive pressure sensors.

Piezoresistive pressure sensors based on flexible, ultrasensitive, and squeezable conductive sponges have recently attracted significant attention. However, the preparation of cost-effective conductive sponges with good stability and wide strain range for pressure sensing remains a challenge. Herein, a conductive poly(vinyl alcohol)/phosphoric acid gel electrolyte@polydimethylsiloxane (PVA/HPO@PDMS) composite was fabricated by impregnating a PDMS sponge into a PVA/HPO gel electrolyte.

Sensitive immunoassay of cardiac troponin I using an optimized microelectrode array in a novel integrated microfluidic electrochemical device.

A sensitive and portable microfluidic electrochemical array device (μFED) was developed for the immunoassay of trace amounts of human cardiac troponin I (cTnI), which is an attractive biomarker for acute myocardial infarction (AMI). The classical "sandwich" method was adopted for the immunoassay. The capture antibody was immobilized using a self-assembled monolayer (SAM) technique, and the process was reorganized to be compatible with the bonding process.

Effect of film thickness and evaporation rate on co-evaporated SnSe thin films for photovoltaic applications.

SnSe thin films were deposited by a co-evaporation method with different film thicknesses and evaporation rates. A device with a structure of soda-lime glass/Mo/SnSe/CdS/i-ZnO/ITO/Ni/Al was fabricated. Device efficiency was improved from 0.

Reduction of acrylamide level through blanching with treatment by an extremely thermostable L-asparaginase during French fries processing.

Bacterial L-asparaginase catalyzes the hydrolysis of L-asparagine to L-aspartic acid. It is normally used as an antineoplastic drug applied in lymphoblastic leukemia chemotherapy and as a food processing aid in baked or fried food industry to inhibit the formation of acrylamide. The present study demonstrates cloning, expression, and characterization of a thermostable L-asparaginase from Thermococcus zilligii AN1 TziAN1_1 and also evaluates the potential for enzymatic acrylamide mitigation in French fries using this enzyme.

Recent research progress on microbial L-asparaginases.

L-Asparaginases (EC 3.5.1.

Direct electron transfer of glucose oxidase immobilized on a mesoporous silica KIT-6 matrix to screen-printed electrodes.

The direct electron transfer of glucose oxidase (GOx) immobilized on a large-pore mesoporous silica KIT-6 matrix fixed to a screen-printed electrode (SPE) and its application as a disposable biosensor were studied. KIT-6 plays a vital role in this method through immobilizing GOx and facilitating the electron communication between the active centers of GOx and the surface of the SPE. GOx immobilized on KIT-6 maintains its bioactivity and structure and displays stable and well-defined redox peaks with a formal potential of -428 mV (vs.

Electrochemical detection of DNA hybridization by using a zirconia modified renewable carbon paste electrode.

A simple, polishable and renewable DNA biosensor was fabricated based on a zirconia modified carbon paste electrode. Zirconia was mixed with graphite powder and paraffin wax to produce the paste for the electrode, and response-optimized at 56% graphite powder, 19% ZrO(2) and 25% paraffin wax. An oligonucleotide probe with a terminal 5'-phosphate group was attached to the surface of the electrode via the strong affinity of zirconia for phosphate groups.