Publications by authors named "Shaofei Li"

DHAV-3 is one of the main causative agents of duck viral hepatitis (DVH), an acute and highly lethal infectious disease in duck industry. However, the understanding of the pathogenesis of this virus in ducklings is limited. To dissect the molecular characteristics associated with pathobiology of ducklings to DHAV-3, we applied single-cell RNA-sequencing approach to profile the transcriptome of 1.

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  • Intervertebral disc degeneration (IVDD) leads to lower back pain and involves loss of specific cells and degradation of the supporting structure, influenced by factors like inflammation and oxidative stress.
  • The glutathione (GSH) redox system serves as a crucial antioxidant in cells, combating oxidative stress by converting harmful substances into less dangerous forms.
  • Research highlights GSH's role in various types of cell death linked to IVDD, and exploring small molecule compounds that influence GSH levels could offer new strategies for preventing or slowing IVDD progression.
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Heterostructure engineering provides versatile platforms for exploring exotic physics and enhancing the device performance through interface coupling. Despite the rich array of physical phenomena presented by heterostructures composed of semiconductor and metal van der Waals materials, significant gaps remain in understanding their optical, thermal, and electronic properties. Here, we demonstrate that the valley pseudospin and electron-phonon coupling in monolayer WSe are significantly influenced by interface coupling with 1T-VSe.

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Magnetic 2D materials offer a promising platform for manipulating quantum states at the nanoscale. Recent studies have underscored the significant influence of 2D magnetic materials on the optical behaviors of transition-metal dichalcogenides (TMDs), revealing phenomena such as interlayer exciton-magnon interactions, magnetization-dependent valley polarization, and an enhanced Zeeman effect. However, the controlled manipulation of anisotropic optical properties in TMDs via magnetism remains challenging.

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  • The study explores how light interacts with moiré superlattices, which could improve technologies in photonics, optoelectronics, and valleytronics.
  • Researchers developed twisted WSe/WSe/SiP structures to show that these superlattices can exhibit a high degree of optical anisotropy, with a polarization degree of about 70% due to uneven charge distribution.
  • They also revealed that applying a magnetic field can modify the polarization state, resulting in changes to the polarization angle and degree, highlighting a new way to manipulate optical properties in moiré superlattices through engineering.
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Unlabelled: (), a facultative intracellular bacterium, is an important zoonotic pathogen that causes abscesses and pyogenic granulomas. The relationship between gut microbiota and host health or diseases has received increasing attention. However, the role of gut microbiota in the process of infection is still unclear.

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  • IV-V two-dimensional materials are key for polarization-sensitive and angle-resolved devices due to their unique directional properties.
  • Researchers used a diamond anvil cell and various measurements to explore the effects of pressure on phonon behavior in SiP flakes, discovering an unusual phonon hardening within a broader softening region.
  • The study showed that applying pressure significantly enhances the degree of polarization in SiP flakes, providing insights into high-pressure phonon changes and methods to optimize the performance of anisotropic 2D materials.
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  • ACL tears are common injuries in sports, often leading to cartilage damage which affects both physical health and mental well-being.
  • Recent research suggests that procyanidins may be effective in repairing cartilage injuries due to their anti-inflammatory and antioxidant properties.
  • The article summarizes the mechanisms and clinical significance of procyanidins in cartilage repair, offering new insights and potential future applications in treating ACL-related cartilage damage.
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  • Duck hepatitis A virus genotype 3 (DHAV-3) significantly impacts the duck industry in China, leading to substantial economic losses.
  • Research involved sequencing the whole transcriptome of susceptible and resistant Pekin ducklings at various time points post-infection, revealing thousands of differentially expressed genes, miRNAs, and lncRNAs.
  • The study highlights the complex interactions of ncRNAs (non-coding RNAs) in regulating immune and metabolic responses during DHAV-3 infection, pointing to potential new treatment targets for infected ducks.
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Currently, the only available commercial vaccines for (ORFV) are live attenuated vaccines, which present a potential risk of reversion to virulence. Therefore, understanding the pathogenic mechanisms of different virulent strains of ORFV and host immune responses triggered by these viruses is crucial for developing new vaccines and interventions. In this study, we found that the attenuated strain downregulates the host innate immune response and antiviral activity.

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Two-dimensional (2D) semiconductors featuring low-symmetry crystal structures hold an immense potential for the design of advanced optoelectronic devices, leveraging their inherent anisotropic attributes. While the synthesis techniques for transition metal dichalcogenides (TMDs) have matured, a promising avenue emerges: the induction of anisotropy within symmetric TMDs through interlayer van der Waals coupling engineering. Here, we unveil the creation of heterostructures (HSs) by stacking highly symmetric MoSe with low-symmetry ReS, introducing artificial anisotropy into monolayer MoSe.

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The aqueous micro batteries (AMBs) are expected to be one of the most promising micro energy storage devices for its safe operation and cost-effectiveness. However, the performance of the AMBs is not satisfactory, which is attributed to strong interaction between metal ions and the electrode materials. Here, the first AMBs are developed with NH as charge carrier.

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Moiré superlattices have emerged as a promising platform for investigating and designing optically generated excitonic properties. The electronic band structure of these systems can be qualitatively modulated by interactions between the top and bottom layers, leading to the emergence of new quantum phenomena. However, the inhomogeneities present in atomically thin bilayer moiré superlattices created by artificial stacking have hindered a deeper understanding of strongly correlated electron properties.

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Moiré superlattices induced by twisted van der Waals (vdW) heterostructures or homostructures have recently gained significant attention due to their potential to generate exotic strong-correlation electronic and phonon phenomena. However, the lack of dynamic tuning for interlayer coupling of moiré superlattices hinders a thorough understanding and development of the moiré correlation state. Here, we present a dynamic tuning method for twisted WSe/WSe homobilayers using a diamond anvil cell (DAC).

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Orf virus (ORFV), also known as infectious pustular virus, leads to an acute contagious zoonotic infectious disease. ORFV can directly contact and infect epithelial cells of skin and mucosa, causing damage to tissue cells. So far, the pathway of ORFV entry into cells is unclear.

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The investigation of in-plane two-dimensional (2D) anisotropic materials has garnered significant attention due to their exceptional electronic, optical, and mechanical characteristics. The anisotropic optical properties and angle-dependent photodetectors based on 2D anisotropic materials have been extensively studied. However, novel in-plane anisotropic materials still need to be explored to satisfy for distinct environments and devices.

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  • Contagious ecthyma (CE), caused by the orf virus, primarily affects sheep and goats, leading to significant economic losses for farmers due to livestock market value impacts.
  • Two strains of the orf virus, FX and LX, were isolated from locations in China, showing distinct genetic variations and clustering into main domestic types, with significant viral populations observed mostly in India and China between 2007 and 2018.
  • The study highlights key genes of the virus with a focus on their evolutionary patterns and potential for vaccine development, as some viral epitopes were predicted for further testing.
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In this work, we investigate the polarization of the excitonics valley in MoS-WS heterostructures using circular polarization-resolved photoluminescence. The valley polarization is the largest (≈28.45%) in the 1L-1L MoS-WS heterostructure and the polarizability of A decreases as the number of WS layers increases.

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The stacking of twisted two-dimensional (2D) layered materials has led to the creation of moiré superlattices, which have become a new platform for the study of quantum optics. The strong coupling of moiré superlattices can result in flat minibands that boost electronic interactions and generate interesting strongly correlated states, including unconventional superconductivity, Mott insulating states, and moiré excitons. However, the impact of adjusting and localizing moiré excitons in Van der Waals heterostructures has yet to be explored experimentally.

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Monolayer transition metal dichalcogenides (TMDs) have a crystalline structure with broken spatial inversion symmetry, making them promising candidates for valleytronic applications. However, the degree of valley polarization is usually not high due to the presence of intervalley scattering. Here, we use the nanoindentation technique to fabricate strained structures of WSe on Au arrays, thus demonstrating the generation and detection of strained localized excitons in monolayer WSe.

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The exploration of moiré superlatticesholds promising potential to uncover novel quantum phenomena emerging from the interplay of atomic structure and electronic correlation . However, the impact of the moiré potential modulation on the number of twisted layers has yet to be experimentally explored. Here, this work synthesizes a twisted WSe homotrilayer using a dry-transfer method and investigates the enhancement of the moiré potential with increasing number of twisted layers.

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The purpose is to introduce a novel scaphoid screw placement surgery based on a novel three-dimensional (3D) printing guiding template through dorsal approach, and to evaluate the clinical feasibility and accuracy. The diagnose of scaphoid fracture was confirmed by Computed Tomography (CT) scanning, and subsequently the CT scanning data was input into a three-dimension imaging system(Hongsong software, China). An individualized 3D skin surface template with a guiding hole was printed.

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Moiré superlattices in twisted van der Waals materials offer a powerful platform for exploring light-matter interactions. The periodic moiré potentials in moiré superlattices can induce strongly correlated quantum phenomena that depend on the moiré potential associated with interlayer coupling at the interface. However, moiré superlattices are primarily prepared by mechanical exfoliation and manual stacking, where the transfer methods easily cause interfacial contamination, and the preparation of high-quality bilayer 2D materials with small twist angles by growth methods remains a significant challenge.

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Hydrogenous environments put forward new requirements to refractories for the hydrogen metallurgy field. The temperature and impurities in refractories played an important role in stability. A commercial brown corundum with many impurities was adopted as a raw material, thermodynamic calculations and reduction experiments of the brown corundum by high-purity hydrogen (99.

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Moiré superlattices offer a fascinating platform for designing the properties of optical excitons. The moiré pattern can generate an ordered exciton array in space, making it possible for topological excitons and quantum emitters. Recently, evidence of moiré excitons in the twisted heterostructures of TMDs has been widely reported.

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