Rete anomaly of the middle cerebral artery: case series of 13 patients from the Northeastern United States.

Background: Rete middle cerebral artery (MCA) is a rare anomaly of the intracranial circulation that mimics congenital Moyamoya disease (MMD). Similar to MMD, it is reported almost exclusively in East-Asian ethnicities. Here, we report 13 patients with rete MCA anomaly from a predominantly non-Asian background in the USA.

Impact of carotid tortuosity on outcome after endovascular thrombectomy.

Background And Objectives: Endovascular thrombectomy (EVT) is efficacious in patients with large vessel occlusion stroke (LVO). We explored whether internal carotid (ICA) tortuosity increases the technical difficulty of EVT thereby lowering the chances of successful recanalization and favorable outcomes.

Patients And Methods: Consecutive patients with LVO and patent ICAs who underwent EVT were included.

Blood Biomarkers for Traumatic Brain Injury: A Quantitative Assessment of Diagnostic and Prognostic Accuracy.

Blood biomarkers have been explored for their potential to provide objective measures in the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are best for diagnosis and prognosis in different severities of TBI. Here, we compare existing studies on the discriminative abilities of serum biomarkers for four commonly studied clinical situations: detecting concussion, predicting intracranial damage after mild TBI (mTBI), predicting delayed recovery after mTBI, and predicting adverse outcome after severe TBI (sTBI).

Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis.

Objectives: TSLP has been shown to be associated with eosinophilic esophagitis (EoE). Specifically, children with EoE often have the nucleotides AA or AG instead of GG at the single nucleotide polymorphism position RS3806932. Presently, the phenotypic characteristics in EoE children with the TSLP EoE risk allele are unknown.

Elevated expression of activated T2 cells and milk-specific T2 cells in milk-induced eosinophilic esophagitis.

Background: Eosinophilic esophagitis (EoE) is an allergic inflammatory disease that is triggered by food allergens and characterized by progressive esophageal dysfunction. Esophageal biopsy specimens are characterized by eosinophilia and expression of T2 cytokines.

Objective: To ascertain whether T2 cells can exist in the peripheral blood in patients with milk-induced EoE.

Perisaccadic Receptive Field Expansion in the Lateral Intraparietal Area.

Humans and monkeys have access to an accurate representation of visual space despite a constantly moving eye. One mechanism by which the brain accomplishes this is by remapping visual receptive fields around the time of a saccade. In this process a neuron can be excited by a probe stimulus in the current receptive field, and also simultaneously by a probe stimulus in the location that will be brought into the neuron's receptive field by the saccade (the future receptive field), even before saccade begins.

A multilayered story of memory retrieval.

The successful retrieval of learned visual associations requires coordination of multiple brain regions involved in the encoding and association of visual images. In this issue of Neuron, Takeda et al. (2015) use a combination of modern recording and analytical methods to eavesdrop on this process.

Covert attention regulates saccadic reaction time by routing between different visual-oculomotor pathways.

Covert attention modulates saccadic performance, e.g., the abrupt onset of a task-irrelevant visual stimulus grabs attention as measured by a decrease in saccadic reaction time (SRT).