A plant virus manipulates both its host plant and the insect that facilitates its transmission.

Tomato yellow leaf curl virus (TYLCV), a devastating pathogen of tomato crops, is vectored by the whitefly , yet the mechanisms underlying TYLVC epidemics are poorly understood. We found that TYLCV triggers the up-regulation of two β-myrcene biosynthesis genes in tomato, leading to the attraction of nonviruliferous . We also identified BtMEDOR6 as a key whitefly olfactory receptor of β-myrcene involved in the distinct preference of MED for TYLCV-infected plants.

Functional Divergence of Plant-Derived Thaumatin-Like Protein Genes in Two Closely Related Whitefly Species.

The recent discovery that various insects have acquired functional genes through horizontal gene transfer (HGT) has prompted numerous studies into this puzzling and fascinating phenomenon. So far, horizontally transferred genes are found to be functionally conserved and largely retained their ancestral functions. It evidently has not yet been considered that horizontally transferred genes may evolve and can contribute to divergence between species.

Wernicke's encephalopathy in a terminally ill patient with primary cervical cancer: A case report and literature review.

Wernicke's encephalopathy (WE) is an acute or subacute neuropsychiatric condition associated with thiamine deficiency that is more often seen in cases of alcohol abuse. The current study presents a rare case of primary cervical cancer complicated by WE. A 44-year-old woman who underwent a laparoscopic radical hysterectomy with endoscopic pelvic lymphadenectomy for primary cervical adenocarcinoma in 2014 developed multiple metastases in the pelvic and abdominal cavities, right iliopsoas muscle and iliac wing 2 years post-surgery.

Drug-induced autoimmune-like hepatitis: A disproportionality analysis based on the FAERS database.

Background: Drug-induced autoimmune-like hepatitis (DI-ALH) is a potentially life-threatening condition that can lead to acute liver failure and necessitate liver transplantation. While the association between certain drugs and DI-ALH has been documented, a comprehensive analysis of drug-related signals in a large, real-world pharmacovigilance database is lacking. This study aimed to systematically identify drugs linked to DI-ALH by analyzing adverse event reports from the U.

Silencing of the plant-derived horizontally transferred gene BtSC5DL effectively controls Bemisia tabaci MED.

Background: The whitefly Bemisia tabaci is a notorious agricultural pest known for its ability to cause significant crop damage through direct feeding and virus transmission. Its remarkable adaptability and reproductive capacity are linked to its ability to acquire and integrate horizontally transferred genes (HTGs) into its genome. These HTGs increase the physiological and metabolic capacities of this pest, including cholesterol synthesis, which is critical for its survival and reproductive success.

Overexpression of from Bunge Enhanced Drought and Salt Tolerance by Improving ROS-Scavenging Capability.

() genes play a crucial role in the response to abiotic stress and are important target genes for research on plant stress tolerance mechanisms. Bunge is a promising candidate tree species for investigating the tolerance mechanism of woody plants against abiotic stress. In our previous study, was identified as being associated with seed drought tolerance.

Performance assessment of public transport networks: An AHP-ANP approach.

Multi-criteria decision-making (MCDM) methods have been extensively employed by researchers in the public transport (PT) sector. While many studies utilize a single MCDM method, employing multiple MCDM methods can achieve more robust results. Furthermore, integrated MCDM methods have the potential to address the weaknesses and limitations inherent in single MCDM method.

Expression reduction and a variant of a P450 gene mediate chlorpyrifos resistance in Tetranychus urticae Koch.

Introduction: Understanding how insects and mites develop resistance to chlorpyrifos is crucial for effective field management. Although extensive research has demonstrated that T. urticae exhibits high resistance to chlorpyrifos, the specific resistance mechanism remains elusive.

Characterization and Performance Evaluation of Liquid Biodegradable Mulch Films and Its Effects on Peanut Cultivation.

With the development of material science and increasing awareness of ecological environmental protection, liquid biodegradable mulch films (LBDMs) have garnered significant public interest. In this research, new LBDMs were developed using hydrophobically modified polymer materials, surfactants, and photosensitive catalysts. Characterization by scanning electron microscopy (SEM) revealed good material compatibility.

A midgut transcriptional regulatory loop favors an insect host to withstand a bacterial pathogen.

Mounting evidence suggests that insect hormones associated with growth and development also participate in pathogen defense. We have discovered a previously undescribed midgut transcriptional control pathway that modulates the availability of 20-hydroxyecdysone (20E) in a worldwide insect pest (), allowing it to defeat the major virulence factor of an insect pathogen (Bt). A reduction of the transcriptional inhibitor (PxDfd) increases the expression of a midgut microRNA (miR-8545), which in turn represses the expression of a newly identified ecdysteroid-degrading glucose dehydrogenase (PxGLD).

Hotspots and trends of risk factors in gastric cancer: A visualization and bibliometric analysis.

Background: The lack of specific symptoms of gastric cancer (GC) causes great challenges in its early diagnosis. Thus it is essential to identify the risk factors for early diagnosis and treatment of GC and to improve the survival rates.

Aim: To assist physicians in identifying changes in the output of publications and research hotspots related to risk factors for GC, constructing a list of key risk factors, and providing a reference for early identification of patients at high risk for GC.

Sensitive, Low-Background-Signal miRNA Analysis via the Self-Priming-Initiated Color Reaction Loaded on a Rolling Circle Amplification Product.

MicroRNAs (miRNAs) have been regarded as potential biomarkers in evaluating various diseases, such as pregnancy-induced hypertension and cancers. However, sensitive and reliable miRNA detection is still a challenge due to the low amplification efficiency and high background signal. Herein, we developed a colorimetric method for miRNA detection utilizing the self-priming-initiated color reaction loaded on a rolling circle amplification (RCA) product.

Silencing of catalase reduces unfavorable low-temperature tolerance capacity in whiteflies.

Background: Temperature is a primary factor that determines the eco-geographical distribution and population development of invasive insects. Temperature stress leads to various negative effects, including excess reactive oxygen species (ROS), and catalase (CAT) is a key enzyme against ROS in the antioxidant pathway. The whitefly Bemisia tabaci MED is a typical invasive pest that causes damage worldwide.

Two horizontally acquired bacterial genes steer the exceptionally efficient and flexible nitrogenous waste cycling in whiteflies.

Nitrogen is an essential element for all life on earth. Nitrogen metabolism, including excretion, is essential for growth, development, and survival of plants and animals alike. Several nitrogen metabolic processes have been described, but the underlying molecular mechanisms are unclear.

A Horizontally Transferred Plant Fatty Acid Desaturase Gene Steers Whitefly Reproduction.

Polyunsaturated fatty acids (PUFAs) are essential nutrients for all living organisms. PUFA synthesis is mediated by Δ12 desaturases in plants and microorganisms, whereas animals usually obtain PUFAs through their diet. The whitefly Bemisia tabaci is an extremely polyphagous agricultural pest that feeds on phloem sap of many plants that do not always provide them with sufficient PUFAs.

A global bibliometric and visualized analysis of the status and trends of gastroparesis research.

Background: Gastroparesis has a substantial impact on the quality of life but has limited treatment options, which makes it a public health concern. No bibliometric studies on gastroparesis have been published thus far. Thus, this article aims to summarize and analyze research hotspots to provide a reference for clinical researchers.

Method for Simulating the Anti-Damage Performance of Consolidation Soil Balls at the Roots of Seedlings during Transportation Using Consolidated Soil Columns.

In the process of landscaping or afforestation in challenging terrain, in order to improve the survival rate of transplanted seedlings, it is necessary to transplant seedlings with a mother soil ball attached. During transportation, the soil ball at the root of the seedlings is very susceptible to breakage due to compression, bumps, and collisions. In order to ensure the integrity of the soil ball of the transplanted seedlings and improve the survival rate of seedlings, a method of chemically enhancing the soil surface strength was employed.

Assessment of the role of an ABCC transporter TuMRP1 in the toxicity of abamectin to Tetranychus urticae.

The rapid evolution of pest resistance threatens the sustainable utilization of bioinsecticides such as abamectin, and so deciphering the molecular mechanisms affecting toxicity and resistance is essential for their long-term application. Historical studies of abamectin resistance in arthropods have mainly focused on mechanisms involving the glutamate-gated chloride channel (GluCl) targets, with the role of metabolic processes less clear. The two-spotted spider mite, Tetranychus urticae, is a generalist herbivore notorious for rapidly developing resistance to pesticides worldwide, and abamectin has been widely used for its control in the field.

Antennal transcriptome analysis of odorant-binding proteins and characterization of GOBP2 in the variegated cutworm .

Odorant-binding proteins (OBPs) are expressed at extremely high concentrations in the chemo-sensilla lymph of insects and have long been thought to be crucial for delivering the semiochemicals to the odorant receptors. They are represented by multiple classes: general odorant-binding proteins (GOBP1 and GOBP2) and pheromone-binding proteins. In the current study, we identified a total of 35 OBPs in the antennal transcriptome of , a worldwide pest that causes serious damage to various crops.

RNU12 inhibits gastric cancer progression via sponging miR-575 and targeting BLID.

Gastric cancer (GC) is one of the major causes of cancer deaths with 5-year survival ratio of 20%. RNU12 is one of long noncoding RNAs (lncRNAs) regulating the tumor progression. However, how RNU12 affecting GC is not clear.

Expression, affinity, and binding mode analysis of antennal-binding protein X in the variegated cutworm Peridroma saucia (Hübner).

The variegated cutworm Peridroma saucia (Hübner) is a worldwide pest that causes serious damage to many crops. Odorant-binding proteins (OBPs) are small soluble proteins involved in the first step of odorant reception. In moths, antennal-binding protein Xs (ABPXs) represent a main subfamily of classic OBPs.