Providing targeted psychological support to frontline nurses involved in the management of COVID-19: An action research.

Aim: To develop and implement a targeted psychological support scheme for frontline nurses involved in the management of coronavirus disease 2019 (COVID-19).

Background: Nurses play a vital role in managing the ongoing COVID-19 pandemic, while confronting enormous challenges and psychological problems.

Methods: Action research design was adopted to develop and provide a targeted psychological support scheme to 1,496 frontline nurses.

Characterization of the role of esterases in the biodegradation of organophosphate, carbamate, and pyrethroid pesticides.

Ester-containing organophosphate, carbamate, and pyrethroid (OCP) pesticides are used worldwide to minimize the impact of pests and increase agricultural production. The toxicity of these chemicals to humans and other organisms has been widely reported. Chemically, these pesticides share an ester bond in their parent structures.

How to Achieve a Monostable Cassie State on a Micropillar-Arrayed Superhydrophobic Surface.

Superhydrophobic surfaces with a monostable Cassie state possess numerous interesting applications in many fields, such as microfluidics, oil-water separation, drag reduction, self-cleaning, heat dissipation, and so on. How to guarantee a monostable Cassie state of a superhydrophobic surface is still an interesting problem. In this paper, considering the influence of external interferences that may induce the possible wettability transition, the whole wetting process of a droplet on a trapezoidal micropillar-arrayed superhydrophobic surface is divided into six possible stages.

Comprehensive analysis of glutathione peroxidase-1 (GPX1) expression and prognostic value in three different types of renal cell carcinoma.

Background: Glutathione peroxidase-1 (GPX1) is generally expressed in tissues with high oxygen tension such as the kidneys and lungs, and its main function is to degrade reactive oxygen species (ROS) and protect cells from oxidative stress. Studies have shown that GPX1 is upregulated in many tumor tissues and is closely related to tumor progression and metastasis. This study aimed to explore the possibility of GPX1 as a biomarker for kidney chromophobe cell carcinoma (KICH), kidney renal papillary cell carcinoma (KIRP), and kidney renal clear cell carcinoma (KIRC).

Binding interaction of glyphosate with glyphosate oxidoreductase and C-P lyase: Molecular docking and molecular dynamics simulation studies.

Widespread application of glyphosate poses a threat to living organisms. Microbial strains are able to degrade glyphosate via contrasting metabolic pathways with the help of enzymes. Glyphosate oxidoreductase (GOX) and C-P lyase are the key enzymes for the biodegradation of glyphosate and its intermediate metabolite aminomethylphosphonic acid (AMPA) in microbes.

Insights into the microbial degradation and catalytic mechanisms of chlorpyrifos.

Chlorpyrifos is extensively used worldwide as an insecticide to control various insect pests. Long-term and irregular applications of chlorpyrifos have resulted in large-scale soil, groundwater, sediment, and air pollution. Numerous studies have shown that chlorpyrifos and its major intermediate metabolite 3,5,6-trichloropyridinol (TCP) accumulate in non-target organisms through biomagnification and have a strong toxic effect on non-target organisms, including human beings.

The mechanical property and microscopic deformation mechanism of nanoparticle-contained graphene foam materials under uniaxial compression.

Nanoparticle-contained graphene foams have found more and more practical applications in recent years, which desperately requires a deep understanding on basic mechanics of this hybrid material. In this paper, the microscopic deformation mechanism and mechanical properties of such a hybrid material under uniaxial compression, that are inevitably encountered in applications and further affect its functions, are systematically studied by the coarse-grained molecular dynamics simulation method. Two major factors of the size and volume fraction of nanoparticles are considered.

Age-Related Immune Profile of the T Cell Receptor Repertoire, Thymic Recent Output Function, and miRNAs.

Background: T cell immunity plays a central role in the body's defense system, including maintaining homeostasis and preventing tumorigenesis and viral infection. Immune system functions degenerate with age, leading to immune senescence. Physiologically, immune senescence is characterized by a decrease in T cell receptor diversity, naive T cell deficiency, and alterations in T cell immune-related miRNAs.

Volunteer nurses' learning experiences in Ludian County, Yunnan, China: Implication for public health nursing education in a disaster.

Objective: To describe the learning impacts made by graduate nurse volunteers who worked in a field hospital 1 month following the 2014 Ludian earthquake in Yunnan, China.

Methods: A qualitative descriptive approach was adopted. The volunteers were 23 final year part-time students enrolled in the Master of Science in Disaster Nursing program offered by the School of Nursing.

Clinical features, risk factors, and clinical burden of acute kidney injury in older adults.

Few epidemiologic studies on acute kidney injury (AKI) have focused on the older adult population. This study investigated the clinical features, risk factors, and clinical burden in this population. A retrospective observational study was performed with the clinical data of inpatients at Guangdong Geriatrics Institute from 1 August 2012, to 31 December 2016.

Biotransformation of perfluoroalkyl acid precursors from various environmental systems: advances and perspectives.

Perfluoroalkyl acids (PFAAs) are widely used in industrial production and daily life because of their unique physicochemical properties, such as their hydrophobicity, oleophobicity, surface activity, and thermal stability. Perfluorosulfonic acids (PFSAs) and perfluorocarboxylic acids (PFCAs) are the most studied PFAAs due to their global occurrence. PFAAs are environmentally persistent, toxic, and the long-chain homologs are also bioaccumulative.

Impact of parathyroidectomy on left ventricular function in end stage renal disease patients.

Background: Secondary hyperparathyroidism (SHPT) is a common complication in end-stage renal disease (ESRD) patients, and parathyroidectomy (PTX) is an effective treatment intervention of SHPT. However, the curative impact of PTX on left ventricular function still remains incompletely understood. To evaluate the impact of parathyroidectomy on left ventricular function in ESRD patients, we conducted this retrospective study.

New insights into the degradation of synthetic pollutants in contaminated environments.

The environment is contaminated by synthetic contaminants owing to their extensive applications globally. Hence, the removal of synthetic pollutants (SPs) from the environment has received widespread attention. Different remediation technologies have been investigated for their abilities to eliminate SPs from the ecosystem; these include photocatalysis, sonochemical techniques, nanoremediation, and bioremediation.

Integrating pathology, chromosomal instability and mutations for risk stratification in early-stage endometrioid endometrial carcinoma.

Background: Risk stratifications for endometrial carcinoma (EC) depend on histopathology and molecular pathology. Histopathological risk stratification lacks reproducibility, neglects heterogeneity and contributes little to surgical procedures. Existing molecular stratification is useless in patients with specific pathological or molecular characteristics and cannot guide postoperative adjuvant radiotherapies.

Increased Expression of TIGIT/CD57 in Peripheral Blood/Bone Marrow NK Cells in Patients with Chronic Myeloid Leukemia.

The antitumor activity of NK cells in patients with chronic myeloid leukemia (CML) is inhibited by the leukemia microenvironment. Recent studies have identified that the expression of TIGIT, CD57, and KLRG1 is related to the function, maturation, and antitumor capabilities of NK cells. However, the characteristics of the expression of these genes in the peripheral blood (PB) and bone marrow (BM) from patients with CML remain unknown.

Dissolving the high-cost with acidity: A happy encounter between fluidized struvite crystallization and wastewater from activated carbon manufacture.

Production of wood-based activated carbon (WAC) generates large volume of highly acidic and phosphate-rich wastewater. Currently, the routine treatment (i.e.

Plastic Deformation and Hardening Mechanisms of a Nano-twinned Cubic Boron Nitride Ceramic.

A very interesting experimental finding shows that a nano-twinned cubic boron nitride (NT-cBN) ceramic has size-dependent hardness. In order to reveal the hardening mechanism of NT-cBN, the plastic deformation mechanism of single-crystalline cubic boron nitride (SC-cBN) under nano-indentation is first studied, and then that of NT-cBN is further investigated using atomistic simulations with a parameter-modified Tersoff potential. It is found that the plastic deformation of SC-cBN under nano-indentation is mainly attributed to serial dislocation behaviors, such as the formation of dislocation embryos, shear loops, and prismatic loops.

Malignant Gastrointestinal Neuroectodermal Tumors: Clinicopathological and Prognostic Features of 96 Patients.

Purpose: Gastrointestinal neuroectodermal tumors (GNETs) are uncommon malignant tumors derived from ectodermal primitive neural cells.

Patients And Methods: We retrospectively analyzed 2 GNET cases at our hospital and the remaining 94 cases in the literature to determine clinicopathological prognostic factors.

Results: The patients had a mean age of 36 years and a median tumor size of 4.

Degradation of Acephate and Its Intermediate Methamidophos: Mechanisms and Biochemical Pathways.

Acephate is an organophosphate pesticide that has been widely used to control insect pests in agricultural fields for decades. However, its use has been partially restricted in many countries due to its toxic intermediate product methamidophos. Long term exposure to acephate and methamidophos in non-target organisms results in severe poisonous effects, which has raised public concern and demand for the removal of these pollutants from the environment.

Characterization of a Novel Quorum-Quenching Bacterial Strain, HN-8, and Its Biocontrol Potential against Black Rot Disease Caused by pv. .

Diffusible signal factor (DSF) is a type of unsaturated fatty acid, with a chemical structure of 11-methyl-2-dodecylene acid. DSF is widely conserved in a variety of Gram-negative bacterial pathogens and is involved in the regulation of pathogenic virulence. Quorum quenching (QQ) is a promising strategy for preventing and controlling quorum sensing (QS)-mediated bacterial infections by interfering with the QS system of pathogens.

[Analysis of intestinal flora in patients with chronic rhinosinusitis based on highthroughput sequencing].

Objective: To investigate the changes in diversity, relative abundance and distribution of intestinal flora in patients with chronic rhinosinusitis and nasal polyps (CRSwNP) using high-throughput sequencing technology identify the intestinal flora significantly related to pathogenesis and progression of CRSwNP.

Methods: Ten patients with CRSwNP hospitalized in the Department of Otolaryngology-Head and Neck Surgery of Guangdong Provincial People's Hospital were selected as the case group with 10 healthy volunteers recruited in the same period as the control group. Fecal genomic DNA extraction kit was used to extract the DNA in the fecal samples, and the DNA fragment length was measured and quantified.

Whole-Genome Sequencing Analysis of Quorum Quenching Bacterial Strain QL-1 Identifies the FadY Enzyme for Degradation of the Diffusible Signal Factor.

The diffusible signal factor (DSF) is a fatty acid signal molecule and is widely conserved in various Gram-negative bacteria. DSF is involved in the regulation of pathogenic virulence in many bacterial pathogens, including pv. ().

Facile fabrication of cellulose/polyphenylene sulfide composite separator for lithium-ion batteries.

As an indispensable component, separator is close related to electrochemical performance and safety of lithium-ion batteries (LIBs). However, the current widely applied polyolefin microporous separator impedes the development of high power LIBs due to poorer electrolyte wettability and inferior thermal stability. Herein, heat-resistant polyphenylene sulfide (PPS) fibers and cellulose fibers (CFs) are adopted to fabricate a novel composite separator (CFs/PPS) via a facile papermaking process.

Diagnostic value of macrophage inhibitory cytokine 1 as a novel prognostic biomarkers for early gastric cancer screening.

Background: Early diagnosis is very important to improve the survival rate of patients with gastric cancer (GC), especially in asymptomatic participants. However, low sensitivity of common biomarkers has caused difficulties in early screening of GC. In this study, we explored whether MIC-1 can improve the detection rate of early GC.