Publications by authors named "ShaoCheng Zhang"

Invasive fungal infections (IFIs) pose a significant threat to immunocompromised individuals, leading to considerable morbidity and mortality. Prompt and accurate diagnosis is essential for effective treatment. Here we develop a rapid molecular diagnostic method that involves three steps: fungal enrichment using affinity-magnetic separation (AMS), genomic DNA extraction with silicon hydroxyl magnetic beads, and detection through a one-pot system.

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  • Fishborne trematode (FBT) parasites are globally significant but not thoroughly researched, particularly their development and identification in metacercariae form.
  • A study in Qiqihar found that 61.8% of 600 specimens were infected with three types of trematode metacercariae, with varying infection rates across different months.
  • The research indicates that co-infections are common and highlights the seasonal variations in infection rates, suggesting a need for future studies on their morphological characteristics and genetic sequencing for better understanding of FBT's ecological impact.
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  • - The study investigates the relationship between the Chinese visceral adiposity index (CVAI) and the production of neutralizing antibodies (NAb) after vaccination against SARS-CoV-2, highlighting the importance of understanding how visceral fat affects vaccine efficacy.
  • - Health workers who were part of the study showed a median NAb titer of 12.94 AU/mL post-vaccination, with those in the CVAI dysfunction group having significantly lower NAb levels and higher inflammation markers compared to the reference group.
  • - The findings suggest that high CVAI could hinder NAb production through immune dysfunction and chronic inflammation, emphasizing the need for targeted vaccination strategies for individuals with high visceral adiposity to enhance overall vaccination effectiveness against COVID-
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Low Na and electron diffusion kinetics severely restrain the rate capability of MoS as anode for sodium-ion batteries (SIBs). Slow phase transitions between 2H and 1T, and from NaMoS to Mo and NaS as well as the volume change during cycling, induce a poor cycling stability. Herein, an original Fe single atom doped MoS hollow multishelled structure (HoMS) is designed for the first time to address the above challenges.

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Air particulate matter (PM) is an essential risk factor for lipid metabolism disorders. However, the underlying mechanism remains unclear. In this cross-sectional study, 216 healthcare workers were recruited to estimate the associations among the daily exposure dose (DED) of air PM, innate immune cells, and plasma lipid levels.

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In single-atom catalysts (SACs), the complexity of the support anchoring sites creates a vast diversity of single-atom species with varied coordination environments. To date, the quantitative distribution of these diverse single-atom species in a given SAC has remained elusive. Recently, CeO-supported metal SACs have been extensively studied by modulating their local environments via numerous synthetic strategies.

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  • The study investigates how obesity affects the production of neutralizing antibodies in response to an inactivated SARS-CoV-2 vaccine, given that obesity is a significant risk factor for COVID-19.
  • A total of 239 healthcare workers participated, with results showing that those with obesity had the highest counts of peripheral monocytes and eosinophils, but the lowest neutralizing antibody titers compared to other weight groups.
  • The findings suggest that obesity may contribute to chronic inflammation and lower vaccine-induced antibody responses, indicating a need for tailored vaccination strategies for obese individuals.
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Air pollution is a crucial risk factor for respiratory infection. However, the relationships between air pollution and respiratory infection based on pathogen detection are scarcely explored in the available literature. We detected respiratory infections through patient-based bacterial culture in sputum, obtained hourly data of all six pollutants (PM, PM, SO, NO, CO, and O) from four air quality monitoring stations, and assessed the relationships of air pollutants and respiratory bacterial infection and multi-drug-resistant bacteria.

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Air pollution is a critical risk factor for the prevalence of COVID-19. However, few studies have focused on whether air pollution affects the efficacy of the SARS-CoV-2 vaccine. To better guide the knowledge surrounding this vaccination, we conducted a cross-section study to identify the relationships between air pollutant exposure and plasma neutralizing antibody (NAb) titers of an inactivated SARS-CoV-2 vaccine (Vero cell, CoronaVac, SINOVΛC, China).

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Particulate air pollution is correlated with many respiratory diseases. However, few studies have focused on the relationship between air particulate exposure and respiratory Heamophilus influenzae infection. Therefore, we detected respiratory Heamophilus influenzae infection by bacterial culture of sputum of patients, and we collected particulate air pollution data (including PM and PM) from a national real-time urban air quality platform to analyze the relationship between particulate air pollution and respiratory Heamophilus influenzae infection.

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Lead (Pb) has been proved to exert adverse effect on human cardiovascular system. However, the cardiotoxicity of Pb on children is still unclear. The aim of this study was to evaluate left ventricular (LV) structure and function, by using echocardiographic indices, in order to elucidate the effect of Pb on low-grade inflammation related to left ventricle in healthy preschool children.

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Environmental lead (Pb) exposure can induce dysbacteriosis, impair oral health, and is associated with the development of dental caries. However, the mechanism is unclear. The aim of this study was to explore the effects of Pb toxicity on oral antimicrobial activity in children in an e-waste area.

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As global navigation satellite system (GNSS)stations are sparsely distributed in oceanic area, oceanic areas usually have lower precision than continental areas on a global ionosphere maps (GIM). On the other hand, space-borne observations like satellite altimetry (SA) and ionospheric radio occultation (IRO) have substantial dual-frequency observations in oceanic areas, which could be used for total electron content (TEC) retrieval. In this paper, the Jason-2 SA and Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) IRO products were used to assess the precision of IGS GIM products.

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The oral health of preschool children in an electronic waste (e-waste) area is susceptible to lead (Pb) exposure increasing the risk of dental caries and causing periodontitis and other oral diseases. The aim of the present study is to investigate the relationship between chronic exposure to Pb and oral anti-inflammatory potential of preschool children. For this analysis, 574 preschool children from 2.

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Fine particulate matter ≤2.5 μm (PM) is a prominent global public health risk factor that can cause respiratory infection by downregulating the amounts of antimicrobial proteins and peptides (AMPs). Both salivary agglutinin (SAG) and surfactant protein D (SPD) are important AMPs in respiratory mucosal fluid, providing protection against airway pathogen invasion and infection by inducing microbial aggregation and enhancing pathogen clearance.

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Environmental pollution is a risk factor for kidney dysfunction. However, the combined toxicity of air pollutants on kidney function is scarce. We estimated the relationship between combined toxicity of air pollutants and kidney function among adult women (n = 7071, 18-65 years old) in Mianyang City, Southwest China.

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The Japanese Quasi-Zenith Satellite System (QZSS) is a regional navigation satellite system covering the entire Asia-Oceania region. Except for the standard satellite navigation signals, QZSS satellites also broadcast L6E augmentation signals with real time GNSS precise orbit every 30 s and clock messages every 1 s, which is very important and necessary for Real-Time precise point positioning (RTPPP) applications. In this paper, the MADOCA real-time services derived from L6E augmentation signals were evaluated for both accuracy and availability compared with IGS final products.

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Ambient fine particulate matter (PM) is a risk factor for respiratory diseases. Previous studies suggest that PM exposure may down-regulate airway antimicrobial proteins and peptides (AMPs), thereby accelerating airway pathogen infection. However, epidemiological research is scarce.

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Cell therapy has been shown to be a key clinical therapeutic option for central nervous system diseases or damage. Standardization of clinical cell therapy procedures is an important task for professional associations devoted to cell therapy. The Chinese Branch of the International Association of Neurorestoratology (IANR) completed the first set of guidelines governing the clinical application of neurorestoration in 2011.

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Osteoporosis is a disease that significantly influences life expectancy and quality in humans. Oxidative stress may stimulate bone marrow osteoclast differentiation and inhibit osteoblast (OB) differentiation. OB proliferation and differentiation are affected by the forkhead box O (FoxO)1/β‑catenin signaling pathway.

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The surface protein SdrE, a microbial surface components recognizing adhesive matrix molecule (MSCRAMM) family protein expressed on the surface of Staphylococcus aureus (S. aureus), can recognize human complement regulator Factor H and C4BP, thus making it a potentially promising vaccine candidate. In this study, SdrE278-591 was found to directly affect S.

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Background: Human tissue plasminogen activator (tPA) belongs to the serine protease family. It converts plasminogen into plasmin and is used clinically to treat thrombosis. Human tPA is composed of 527 amino acids residues and contains 17 disulfide bonds.

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Currently, there is a lack of effective therapeutic methods to restore neurological function for chronic complete spinal cord injury (SCI) by conventional treatment. Neurorestorative strategies with positive preclinical results have been translated to the clinic, and some patients have gotten benefits and their quality of life has improved. These strategies include cell therapy, neurostimulation or neuromodulation, neuroprosthesis, neurotization or nerve bridging, and neurorehabilitation.

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The high-mobility group protein (HMO2) of Saccharomyces cerevisiae is a component of the chromatin-remodelling complex INO80, which is involved in double-strand break (DSB) repair. HMO2 can also bind DNA to protect it from exonucleolytic cleavage. Nevertheless, little structural information is available regarding these functions of HMO2.

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