Publications by authors named "Shao-yang Wang"

Hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF) is a complicated syndrome with extremely high short-term mortality. Whether plasma exchange (PE) improves HBV-ACLF outcomes remains controversial. Here, PE-based non-bioartificial liver support system (NB-ALSS) effects on short-term HBV-ACLF patient outcomes were investigated.

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Article Synopsis
  • Portal vein thrombosis (PVT) is a serious issue in cirrhosis patients and is more common in those experiencing acute decompensation (AD), with a prevalence of 9.36% compared to 5.24% in those without AD.
  • Recent PVT was found in 63.37% of patients with cirrhosis and AD, and these patients also had higher rates of variceal bleeding and elevated D-dimer levels.
  • Despite the higher incidence of bleeding and complications, the one-year mortality rate was similar between patients with and without PVT, highlighting the need for preventive measures and regular screenings in vulnerable cirrhosis patients.
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Background: Neurofilament light chain (NFL) as a potential biomarker of neurodegenerative diseases has been studied in a number of studies. Thus, a comprehensive meta-analysis is warranted to assess NFL performance in neurodegenerative diseases.

Objective: To assess the performance of NFL in blood and cerebrospinal fluid (CSF) as a biomarker for neurodegenerative diseases.

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Article Synopsis
  • Definitions of acute-on-chronic liver failure (ACLF) differ between Western and Eastern perspectives, with alcoholism and hepatitis B virus (HBV) being the primary causes in their respective regions.
  • A multicenter study in Asia is proposed to establish unified diagnostic criteria and treatment plans for ACLF, given the high prevalence of HBV in the region.
  • The study aims to enroll 2,600 patients from 14 liver centers in China, tracking data and outcomes over a 36-month period for those with chronic liver disease and acute complications.
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A nitrogen deficiency always causes bog bilberry syrup wine to have a poor sensory feature. This study investigated the effect of nitrogen source addition on volatile compounds during bog bilberry syrup wine fermentation. The syrup was supplemented with 60, 90, 120 or 150 mg/L dibasic ammonium phosphate (DAP) before fermentation.

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Aim: To investigate the features of HIV-1-Gag-, Tat-, Rev- and Nef- specific cytotoxic T-lymphocyte (CTL) responses in infected individuals in China.

Methods: The HIV-1-specific CTL responses were analyzed with an IFN-gamma ELISPOT assay by using 220 overlapping peptides spanning the entire HIV-1 Clade B (HIV-1B) and C (HIV-1C) Gag, Tat, Rev and Nef proteins consensus sequences.

Results: For either HIV-1B or HIV-1C, Gag and Nef were preferentially targeted by HIV-1 specific CTLs, Rev and Tat proteins were also recognized to different extent.

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