Granulocyte Colony-Stimulating Factor Improves Endothelial Progenitor Cell-Mediated Neovascularization in Mice with Chronic Kidney Disease.

Patients with chronic kidney disease (CKD) have a higher prevalence of peripheral arterial disease (PAD), and endothelial progenitor cells (EPCs) play a pivotal role. We examined the impact of granulocyte colony-stimulating factor (G-CSF) on EPC function in response to tissue ischemia. Eight-week-old male C57BL/6J male mice were divided into sham operation and subtotal nephrectomy (SNx) groups, received hindlimb ischemic operation after seven weeks, then randomly received G-CSF or PBS intervention for four weeks with weekly follow-ups.

Using artificial intelligence algorithms to predict the overall survival of hemodialysis patients during the COVID-19 pandemic: A prospective cohort study.

Background: Hemodialysis (HD) patients are a vulnerable population at high risk for severe complications from COVID-19. The impact of partial COVID-19 vaccination on the survival of HD patients remains uncertain. This prospective cohort study was designed to use artificial intelligence algorithms to predict the survival impact of partial COVID-19 vaccination in HD patients.

[Effects of Exogenous Microorganism Inoculation on Efficiency and Bacterial Community Structure of Sludge Composting].

In this study, municipal sludge, sawdust, and mushroom residues were used as raw materials for composting, and thermophiles and white-rot fungi were added into the compost in stages. By measuring physicochemical factors, including temperature, pH value, organic matter, water-soluble organic carbon, moisture content, total nitrogen, NH-N, NO-N, and germination index during the composting process, the effect of exogenous bacteria inoculation on the efficiency of compost was determined. By means of high-throughput sequencing technology, the variation of bacterial community structure and the impact of exogenous bacteria inoculation on bacterial community structure during sludge composting were also investigated.