Publications by authors named "Shao-Yang Bu"
Article Synopsis
- The golden pompano (Trachinotus blochii), a commercially important fish species in aquaculture, faces threats from diseases due to rapid farming practices.
- Researchers established a new immortal cell line called GPF (Golden pompano fin cells), which has been successfully cultured over 69 generations, allowing for extensive physiological and pathological studies.
- The GPF cell line was confirmed to be derived from the golden pompano, showed responses to various treatments (like heavy metals and immune triggers), and provided insights into immune response mechanisms, making it a valuable tool for future research.
Molecular and functional characterization of golden pompano (Trachinotus blochii) TBK1 on IFN regulation.
Fish Shellfish Immunol
December 2023
Article Synopsis
- The golden pompano is a commercially important fish in China facing threats from Nervous necrosis virus (NNV), prompting the need for research on its immune system.
- This study focused on the characterization and function of TANK-binding kinase 1 (gpTBK1), which plays a key role in the immune response, particularly in activating interferon production.
- Findings revealed that gpTBK1 is upregulated during NNV infection, interacts with other immune proteins, and is essential for the expression of antiviral genes in golden pompano, highlighting its importance in combating viral threats.
Regulation of the promoter in yellowtail clownfish () by cortisol GRE-dependent GR pathway.
Front Endocrinol (Lausanne)
August 2022
Kisspeptin plays a vital role in mediating the stress-induced reproductive regulation. Cortisol, known as a stress-related hormone, is involved in gonadal development and sexual differentiation by binding with glucocorticoid receptor (GR) to regulate the expression of gene. In the present study, cortisol treatment in yellowtail clownfish () showed that the expression of ( and ) and ( and ) genes were increased significantly.
View Article and Find Full Text PDFKisspeptin system was shown to be a key factor in mediating social stress and reproduction. Yellowtail clownfish, Amphiprion clarkii, is a hermaphrodite fish, whose sex determination and gonadal development are affected by the social status of individuals. The yellowtail clownfish is a fantastic animal model to explore sex determination, but the social status and precise distribution of kiss mRNAs in the brain of this species are unknown.
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