Arecoline inhibits and destabilizes agrin-induced acetylcholine receptor cluster formation in C2C12 myotubes.

Areca nut (Areca catechu) is chewed as a medical and psychoactive food by roughly 10% of the world population. Areca nut chewing may lead to low birth weight, premature delivery and impaired muscle development. Our previous study showed that arecoline, a major alkaloid in the areca nut, inhibited the myogenic differentiation of C2C12 myoblastic cells.

Arecoline inhibits myogenic differentiation of C2C12 myoblasts by reducing STAT3 phosphorylation.

Areca nut (Areca catechu) is chewed regularly as a medical and psychoactive food by about 10% of the world population, in countries including India, Taiwan and parts of Southern Asia. Areca nut chewing during pregnancy has been associated with both lower birth weight and premature birth. Animals of low birth weights showed retardation of muscle development.

A preliminary report on the toxicity of arecoline on early pregnancy in mice.

Areca nut (Areca catechu) is chewed by roughly 10% of the world population, including India, Taiwan and parts of China. Lower mean birth-weight and higher neonatal jaundice were reported in the babies of betel chewing pregnant women in 1982. Although areca nut chewing during pregnancy has been associated with lower birth weight and premature delivery, the mechanism of such complications is not entirely understood.

Rare case of left colic flexure is supplied by a branch from splenic artery--a case report.

A variation of a branch of the splenic artery was reported in a Taiwanese male cadaver during dissection in 1999. This artery arose from the splenic artery and ran inferiolaterally to the area of the left colic flexure. Since left colic flexure is a segment of embryonic hindgut and the splenic artery typically supplies the foregut, the condition in which an artery of foregut crosses midgut to supply an area of the hindgut becomes interesting.