Publications by authors named "Shao-Song Xi"
[Research Progress in Clinical Electrophysiological Assessment of Patients with Sepsis-Associated Encephalopathy].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao
October 2022
Article Synopsis
- Sepsis-associated encephalopathy (SAE) is a condition resulting from infections outside the brain that leads to significant brain damage and has a poor prognosis.
- Diagnosing SAE is challenging due to factors like sedation and mechanical ventilation, which complicate patient assessments.
- This review focuses on electrophysiological methods, like electroencephalography and somatosensory evoked potentials, to enhance the evaluation and diagnosis of SAE in clinical settings.
Article Synopsis
- People can get brain damage when their brain doesn't get enough blood, but cooling down (hypothermia) can help protect the brain cells from dying.
- In a study, scientists found that cooling brain cells made them healthier and stopped some harmful proteins from causing damage.
- The cooling worked by helping a important protein called PTEN, which helps keep the brain cells safe during times when they are not getting enough oxygen and blood.
Article Synopsis
- Scientists are studying how mesenchymal stem cells (MSCs) can help treat severe acute pancreatitis (SAP) by making blood vessels healthier.
- They tested MSCs taken from human umbilical cords that were treated with a chemical called Angiotensin-II to see if they could reduce damage in rats with SAP.
- The results showed that these treated MSCs helped heal the pancreas, improved blood vessel formation, and protected certain cells from dying, showing promise for better treatments for SAP!
Clinical epidemiological studies have shown that there is a link between Parkinson's disease (PD) and cancer, but how PD regulates cancer development remains unknown. In our study, the effect of metabotropic glutamate receptor 5 (mGlu) on hepatoma was explored in a rotenone-induced PD model both in vitro and in vivo. We found that conditioned media derived from MN9D dopaminergic neuronal cells by rotenone-induced toxicity inhibited the growth, migration, invasion and promoted apoptosis of Hepa1-6 cells, which corresponded with decreased expression of mGlu.
View Article and Find Full Text PDFNumerous epidemiological studies suggested that there is a variable cancer risk in patients with Parkinson's disease (PD). However, the underlying mechanisms remain unclear. In the present study, the role of metabotropic glutamate receptor 5 (mGluR5) has been investigated in 6-hydroxydopamine (6-OHDA)-induced PD combined with liver cancer both in vitro and in vivo.
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