Publications by authors named "Shao-Qing Zeng"
Article Synopsis
- Platelets can be influenced by cancer through a process called education, leading to a specific transcriptional profile that can aid in cancer detection, particularly for ovarian cancer.
- A study involving 761 patients with confirmed adnexal masses and 167 healthy controls across multiple countries showed that tumor-educated platelets (TEPs) had a high diagnostic accuracy, with AUCs (area under the curve) ranging from 0.887 to 0.923 in validation cohorts.
- Combining TEPs with the CA125 biomarker further improved detection accuracy, and TEPs showed potential across diverse populations and cancer stages, but further extensive studies are necessary before they can be widely used in clinical settings.
Soaring cases of coronavirus disease (COVID-19) are pummeling the global health system. Overwhelmed health facilities have endeavored to mitigate the pandemic, but mortality of COVID-19 continues to increase. Here, we present a mortality risk prediction model for COVID-19 (MRPMC) that uses patients' clinical data on admission to stratify patients by mortality risk, which enables prediction of physiological deterioration and death up to 20 days in advance.
View Article and Find Full Text PDF[Correlation analysis between multi-slice CT perfusion imaging and microvessel density in ovarian tumors].
Nan Fang Yi Ke Da Xue Xue Bao
November 2009
Objective: To analyze the correlation between the perfusion data and microvessel density (MVD) in ovarian tumors, and investigate the hemodynamic features of the tumors in terms of anatomy and functional CT imaging.
Methods: Six patients with surgically confirmed benign ovarian tumors and 6 with malignant ovarian tumors underwent multi-slice CT perfusion imaging to acquire the perfusion parameters including perfusion, PEI, TTP, BV peak enhancement image(PEI), time to peak(TTP) and blood volume(BV). The tumors were stained and counted by Immunohistochemical staining of the microvessels in the tumor was performed to detect the MVD.
[Atypical magnetic resonance imaging vs pathological findings of leiomyoma in the female reproductive system].
Nan Fang Yi Ke Da Xue Xue Bao
February 2009
Objective: To investigate magnetic resonance imaging (MRI) findings of the atypical leiomyoma in the female reproductive system in comparison with the pathological features of the neoplasms.
Methods: A retrospective analysis of the MRI findings and the pathological features was conducted in 24 cases of atypical leiomyoma involving the female reproductive system.
Results: Atypical leiomyomas were displayed by MRI as solid tumor mass surrounded by cystic degeneration, pseudotumors, or solid mass with homogeneous signal intensity.