Publications by authors named "Shao-Min Ou"

Breast cancer is a high-risk heterogeneous disease with myriad subtypes and complicated biological features. The Cancer Genome Atlas (TCGA) breast cancer database provides researchers with the large-scale genome and clinical data via web portals and FTP services. Researchers are able to gain new insights into their related fields, and evaluate experimental discoveries with TCGA.

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Article Synopsis
  • Previous studies indicated that patients with bipolar depressive disorder (BDd) or unipolar depressive disorder (UDd) exhibit abnormalities in cerebral metabolites due to issues in specific brain regions.
  • A study involving 13 BDd patients, 20 UDd patients, and 20 healthy controls analyzed the concentrations of 5 cerebral metabolites across different subregions of gray matter, including key areas like the medial frontal cortex and anterior cingulate cortex.
  • Results showed significant differences in metabolite levels (like higher glutamate-glutamine in BDd compared to UDd) and highlighted various interactions, suggesting that cerebral metabolite concentrations relate to the severity of the conditions in different brain regions.
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