Reconstruction of three-dimensional objects in layered composite structures from multimode orbital angular momentum.

Because of helical phase wavefront distribution, vortex electromagnetic waves are considered to carry more information and additional degrees of freedom than traditional spherical waves. Therefore, a vortex wave carrying orbital angular momentum (OAM) can improve inversion and imaging accuracy. In this work, we revisit the reconstruction of three-dimensional objects in layered composite structures extended with OAM.

Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.

The tumor suppressor gene p53 is often inactivated in breast cancer cells due to gene mutation or overexpression of its repressors (such as murine double minute 2 and murine double minute X). Inhibitors of murine double minute 2 (MDM2) and murine double minute X (MDMX) could lead to tumor suppression by restoration of p53 activity and such an approach is a promising strategy for future control of breast cancer. This study aimed to investigate the feasibility of the recombinant MDM2 and MDMX inhibitory protein in control of breast cancer in vitro.