Zhongguo Zhong Yao Za Zhi
November 2007
Objective: To find out the optimum extract process for Ligusticum chuanxiong in Gan-ning Granule, and studyed the methods of concentration and dry for the extract.
Method: With the yield of ferulic acid as the assessment index, to optimize the 80% alcohol totalling, extracting times and circumfluence time for extract process by the orthogonal design, to optimize the inlet-air temperature, feed speed and density of feed for spry drying by the orthogonal design.
Result: The optimum procedure was the ferulic acid were extracted for 1 hour with 3 times of 80% alcohol.