Synopsis of recent research by authors named "Shao-Chin Lee"
- Shao-Chin Lee's recent research focuses on the link between environmental toxins, such as cadmium and chromium, and centrosome amplification in human cancers, suggesting that these toxins may promote tumorigenesis through signaling pathways that involve reactive oxygen species (ROS) and other mediators.
- A significant aspect of Lee's work highlights the interplay between diabetes and cancer, demonstrating that diabetes-related factors can trigger centrosome amplification, which may contribute to increased cancer risk and poor prognosis, particularly in colon cancer.
- Lee has also explored novel therapeutic approaches, such as the effects of the antitumor compound clinopodiside A and natural products, including resveratrol, indicating potential pathways for mitigating cancer cell survival and overcoming drug resistance in treatments.