Are bowel symptoms and psychosocial features different in irritable bowel syndrome patients with abdominal discomfort compared to abdominal pain?

Background: The Rome IV criteria eliminated abdominal discomfort for irritable bowel syndrome (IBS), which was previously included in Rome III. There are questions as to whether IBS patients with abdominal discomfort (seen in Rome III but not Rome IV) are different from those with abdominal pain (Rome IV).

Aim: To compare bowel symptoms and psychosocial features in IBS patients diagnosed with Rome III criteria with abdominal discomfort, abdominal pain, and pain & discomfort.

Joint Association of Metabolic Health and Obesity with Ten-Year Risk of Cardiovascular Disease among Chinese Adults.

Objective: This study aims to investigate the association of metabolic phenotypes that are jointly determined by body mass index (BMI) or fat mass percentage and metabolic health status with the ten-year risk of cardiovascular disease (CVD) among Chinese adults.

Methods: Data were obtained from a cross-sectional study. BMI and body fat mass percentage (FMP) combined with the metabolic status were used to define metabolic phenotypes.

Study of Zero-Inflated Regression Models in a Large-Scale Population Survey of Sub-Health Status and Its Influencing Factors.

Objective Sub-health status has progressively gained more attention from both medical professionals and the publics. Treating the number of sub-health symptoms as count data rather than dichotomous data helps to completely and accurately analyze findings in sub-healthy population. This study aims to compare the goodness of fit for count outcome models to identify the optimum model for sub-health study.

Prevalence and Factors Associated with Female Sexual Dysfunction in Beijing, China.

Background: Female sexual dysfunction (FSD) is a highly prevalent and often underestimated problem. However, large-scale, population-based epidemiological surveys of FSD are scarce in China. The present study was conducted to evaluate the prevalence and the potential risk factors of FSD across a selection of social groups in Beijing, China, based on the Female Sexual Function Index (FSFI).

Protein-losing enteropathy in systemic lupus erythematosus: 12 years experience from a Chinese academic center.

Objective: Protein-losing enteropathy (PLE) is a complication in some systemic lupus erythematosus (SLE) patients that is often misdiagnosed. With this study, we provide insight into clinical characteristics, laboratory characteristics, diagnostic tests, risk factors, treatment, and prognosis of the disease.

Methods: A retrospective, case-control study was performed in 44 patients with SLE-related PLE (PLE group) and 88 patients with active SLE (control group) admitted to our care from January 2000-January 2012.

[Analysis of prognostic factors related to triple-negative breast cancer].

Objective: To investigate the prognostic factors related to triple-negative breast cancer (TNBC) by analyzing clinicopathologic characteristics, treatment and prognosis.

Methods: Three hundred and five TNBC patients treated between January 2004 and December 2011 were enrolled and retrospectively reviewed with Kaplan-Meier and Cox proportional hazards models. All patients were females and the age onset were 24-82 years old (the median were 50 years old).

Serum γ-glutamyltransferase and uric acid levels are associated with impaired fasting glucose in adults from Inner Mongolia, China.

Background: Serum γ-glutamyltransferase (GGT) and uric acid (UA) levels are elevated in patients with diabetes or cardiovascular disease. Prediabetes, characterized by impaired glucose tolerance, is an important risk factor for overt diabetes as well as cardiovascular disease. Therefore, the aim of this study was to explore the relationship between GGT, UA and prediabetes in a Chinese population, and provide a scientific basis for the early prevention and treatment of diabetes.

Early biochemical response to ursodeoxycholic acid and long-term prognosis of primary biliary cirrhosis: results of a 14-year cohort study.

Unlabelled: The biochemical response to ursodeoxycholic acid (UDCA) in primary biliary cirrhosis is a strong predictor of long-term outcome and thus facilitates the rapid identification of patients needing new therapeutic approaches. Numerous criteria for predicting outcome of treatment have been studied based on biochemical response to UDCA at 1 year. We sought to determine whether an earlier biochemical response at 3 or 6 months could as efficiently identify patients at risk of poor outcome, as defined by liver-related death, liver transplantation, and complications of cirrhosis.

[Comparative analysis of early diagnostic tools for breast cancer].

Objective: Mammography is the principle imaging modality used for early diagnosis of breast cancer in Western countries. It has not been well-established whether this Western diagnostic modality is adoptable for Chinese women. The aim of this study was to evaluate the respective accuracy of the common diagnostic tools for breast cancer including history-taking, physical examination, ultrasound and mammography.

Ratio of waist circumference to chest circumference is inversely associated with lung function in Chinese children and adolescents.

Background And Objective: In White children, waist circumference (WC) is positively correlated with forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV(1)). Because fat distribution differs among different races, the relationship between WC and lung function in Asian children may differ from that in White children. The present study aimed to examine the effect of WC on ventilatory function in Chinese children.

Birth measurements, family history, and environmental factors associated with later-life hypertensive status.

Background: This birth cohort study was conducted to investigate the contribution of prenatal and antenatal environmental exposures to later-life hypertensive status.

Methods: Two thousand five hundred and three individuals born in 1921-1954 at the Peking Union Medical College Hospital (PUMCH) were targeted; 2,081 (83.1%) participated.

Spirometric standards for healthy children and adolescents of Korean Chinese in northeast China.

In China there are 1,923,842 Korean Chinese, who live mostly (92.27%) in the country's three northeast provinces. In spite of this sizeable number, no spirometric data are available at present on them.

[Prediction of ventilatory function in children and adolescents using backpropagation neural networks].

The aim of this study is to develop backpropagation neural networks (BPNN) for better prediction of ventilatory function in children and adolescents. Nine hundred and ninety-nine healthy children and adolescents (500 males and 499 females) aged 10-18 years, all of the Han Nationality, were selected from Inner Mongolia Autonomous Region, and their heights, weights, and ventilatory functions were measured respectively by means of physical examination and spirometric test. Using the approaches of BPNN and stepwise multiple regression, the prediction models and equations for forced vital capacity (FVC), forced expiratory volume in one second (FEV1), peak expiratory flow (PEF), forced expiratory flow at 25% of forced vital capacity (FEF25%), forced expiratory flow at 50% of forced vital capacity (FEF50%), maximal mid-expiratory flow (MMEF) and forced expiratory flow at 75% of forced vital capacity (FEF75%) were established.

[The relationship between body fat percentage, waist-hip ratio and pulmonary ventilatory function among the adult females in Heilongjiang, in 2008].

Objective: To examine the effect of body fat mass and fat distribution on pulmonary ventilatory function among the adult females.

Methods: Based on the multistage cluster sampling principal, we selected 935 healthy adult females with ages of 19-81 years old in Heilongjiang province to conduct the study. Every 10-years old as a age group.

[Epidemiological study of women adults with mixed urinary incontinence in China].

Objective: To investigate the prevalence and the epidemiological factors of female mixed urinary incontinence (MUI) in China.

Methods: In February to July 2006, 19 024 subjects aged over 20 years old in 6 Chinese regions including Northwest, Southwest, Northern China, Eastern China, Northeast and South China were selected. Questionnaires were used to investigate the general characters and the lower urinary tract symptoms in these subjects.

[Relation between fat mass, fat free mass and ventilatory function in children and adolescents].

The aim of the present study was to evaluate the relation between fat mass (FM), fat free mass (FFM) and ventilatory function in children and adolescents. 1 174 healthy children and adolescents (583 males and 591 females) aged 10-18 years were selected from Heilongjiang Province through random sampling by means of questionnaire and physical examination, and measured for height, weight, waist to hip ratio (WHR), FM, FFM and ventilatory function. The data were analyzed by means of independent-samples t test, Pearson correlation analysis and multi-factors regression analysis.

Relationship between birth head circumference and adulthood quality of life in Chinese people.

Aim: To determine the relationship between birth size and later QOL for Chinese people.

Methods: Birth data of 1074 subjects were obtained from obstetric birth records of Peking Union Medical College Hospital. All subjects are interviewed face to face with the 36-Item Short-Form Health Survey scale by trained investigators.

[Fat mass and fat free mass on ventilatory function in adults].

This study is designed to probe for the effects of fat mass (FM) and fat free mass (FFM) on ventilatory function in adults. 1 307 healthy adults (372 males and 935 females) were selected from some localities of Heilongjiang province through random sampling by means of questionnaire and physical examination and measured for height, weight, waist to hip ratio (WHR), FM, FFM and ventilatory function. The data were analyzed by means of Pearson correlation analysis, independent-samples t test and multi-factors regression analysis.

[Relationship of body mass index, fat free mass index, and fat mass index with inspiratory capacity in adults with normal lung function].

Objective: To study the relationship of inspiratory capacity (IC) with body mass index (BMI), fat free mass index (FFMI), and fat mass index (FMI) in adults with normal lung function.

Methods: Based on a survey on the Chinese physiological constants conducted in Heilongjiang during 2008, we obtained the data of 2,050 adults (921 men and 1,129 women aged 19-81 years) with normal lung function and grouped them according to the standard of classification of body weight recommended by Working Group on Obesity of China. Statistical analysis was performed using Pearson correlation analysis, one-way analysis of variance,and multi-factor regression analysis.

[The relationship between percentage body fat, waist-hip ratio and cardiovascular function in the adult females of Heilongjiang province].

Objective: To analyze the relationship between body fat mass and distribution and cardiovascular function in the adult females of Heilongjiang province.

Methods: Based on the statistic variable random sampling principal, we selected 1903 healthy adult females with ages of 18 - 70 years old in Heilongjiang province to conduct the study. The height, body weight, waist, chest measurement and waist-hip ratio (WHR) were measured.

[Comparison of sub-health status between Tibetan people and Han people].

Objective: To compare the prevalence of sub-health status between Han people and Tibetan people.

Methods: Subjects were selected with two-stage clustering sampling method in Sichuan Province. The sub-health rating scale developed by Chen Qing-shan, et al was employed to assess the sub-health status of subjects.

[Comparison of the systemic vascular resistance and the correlative factors in Han and Korean populations of China.].

In the present study, the differences in systemic vascular resistance (SVR) and the correlated risk factors between Han and Korean residents were investigated. 1 647 Hans and 876 Koreans from Mudanjiang and Hailin areas of Heilongjiang Province were examined with BIOZ Cardio Dynamics Monitor. A series of factors were determined, including SVR, systemic vascular resistance index (SVRI), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), cardiac output (CO), cardiac output index (CI) and heart rate (HR).

Relationship between perinatal characteristics and later activities of daily living in Chinese elderly people.

Background: There are no reports on the association between perinatal characteristics and comprehensive physical function in Chinese elderly people. In this study, we traced 875 subjects who were born at the Peking Union Medical College Hospital (PUMCH) of China from 1921 to 1941. The purpose of this study was to determine the effects of perinatal characteristics on activities of daily living (ADL) function in the geriatric period.

[Efficacy and safety of compound azintamide on dyspepsia symptoms in a multicentre self-controlled trial].

Objective: To investigate the efficacy and safety of compound azintamide on dyspepsia symptoms.

Methods: One hundred and eighty dyspepsia patients were divided into two groups according to dyspepsia symptom related with gastrointestinal disease (group A) or biliary system disease (group B), whose dyspepsia symptom were not improved by the Domperidone 10 mg tid for 2 weeks. Two tablets of compound azintamide were administered orally following a meal, tid for 2 weeks.