Synopsis of recent research by authors named "Shao Chin Lee"
- Shao Chin Lee's recent research primarily focuses on the mechanisms of centrosome amplification (CA) related to various environmental contaminants and diabetes, highlighting their roles in tumorigenesis and cancer progression.
- Notable findings include the identification of reactive oxygen species (ROS) pathways and specific protein interactions that facilitate CA in colon cancer cells due to exposure to cadmium and hexavalent chromium, as well as in diabetic conditions.
- The work also explores how inflammatory processes and advanced glycation end products contribute to CA and cancer, emphasizing the intersection between environmental toxins, metabolic disorders, and cancer biology.
