Glioma Recurrence Versus Radiation Necrosis: Single-Session Multiparametric Approach Using Simultaneous O-(2-18F-Fluoroethyl)-L-Tyrosine PET/MRI.

Purpose: This study aimed to investigate the potential of hybrid gadolinium (Gd)-enhanced F-fluoroethyl-L-tyrosine (F-FET) PET/MRI in distinguishing recurrence from radiation necrosis using simultaneously acquired multiple structural and functional parameters.

Methods: Twenty-six patients (5 female and 21 male patients; mean ± SD age, 51.58 ± 15.

Somatostatin receptor-positive granulomatous inflammation mimicking as meningioma on simultaneous PET/MRI.

Positron imaging with radiolabeled synthetic somatostatin receptor analogs such as Ga DOTATATE (Gallium-68-1,4,7,10-tetraazacyclododecane-N,N',N″,N‴-tetra acetic acid-DPhe1,Tyr3-octreotate) is used for diagnosis and target volume delineation of intracranial meningiomas. We report a case of a somatostatin receptor-positive extra-axial necrotizing granulomatous inflammation mimicking as meningioma on simultaneous Ga DOTATATE PET/MRI. This case illustrates a Ga DOTATATE-positive granuloma bearing a striking resemblance to meningioma.