Publications by authors named "Shanti Chandrasekaran"
Nucleic Acids Res
April 2013
Article Synopsis
- MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression by binding to messenger RNAs, and they are inherited from the mother during fertilization.
- In Drosophila, researchers found that the miRNA dme-miR-34 is present in embryos before zygotic transcription begins, indicating its early role in development and dependence on maternal Dicer-1.
- The study also showed that in zebrafish, maternal miR-34 is crucial for proper neuronal development, as knocking it down led to defects, highlighting its significance in vertebrate embryonic development.
