Publications by authors named "Shanthi M"

Dentistry still faces difficulties in diagnosing oral precancer and cancer, especially when it comes to early phase changes or disease detection, evaluation, and treatment. In essence, oral lumenography is the process of identifying oral lesions using a chemiluminescent light source and a toluidine blue labeling system. Since neoplastic epithelial cells have a changed nuclear-cytoplasmic ratio, acetic acid dehydration brings out this nuclear density and gives the tissue an "acetowhite" look.

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Facial bone fractures are a common occurrence in trauma cases, particularly in India where road traffic accidents contribute significantly. Over the past few years, artificial intelligence (AI) has become a potent instrument to help medical professionals diagnose and treat facial fractures. This study aims to perform a bibliometric analysis, that is, a quantitative and qualitative analysis, of publications focusing on the role of AI in detecting facial bone fractures.

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The interaction between plants and microorganisms plays a major role in plant growth promotion and disease management. While most microorganisms directly influence plant health, some indirectly support growth through pest and disease suppression. Endophytic entomopathogenic fungi are diverse, easily localized, and have long-lasting effects on insect pests.

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Background: Indwelling double-J-stent (DJ stent) kept post-urological procedures may cause urinary tract infections (UTIs) due to polymicrobial biofilm formation and colonisation.

Aims: To determine the incidence and microbiological characteristics of DJ stent related UTIs in a paediatric population.

Methods And Material: Patients under the age of 18 admitted for DJ stent removal following pediatric urological procedures were enrolled into the study.

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Background:  The prevalence of smokeless tobacco, areca nut, and e-cigarette use among university students has raised concerns regarding their potential impact on oral health. Assessing students' knowledge, attitudes, and practices toward these substances is necessary. Understanding these factors can inform targeted interventions and policies promoting oral health among this population.

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Article Synopsis
  • - A new method uses visible light to activate triplet oxygen in reactions between pyrazole amine and phenylglyoxal monohydrate at room temperature, with water acting as both solvent and reagent.
  • - The process relies on several factors including light, a photocatalyst, oxygen, and water, leading to the successful synthesis of various dicarbonylpyrazole amines and pyrazolooxazine derivatives in moderate to good yields.
  • - This technique shows sustainability and environmentally-friendly aspects while demonstrating high selectivity in producing specific compounds, with mechanistic insights obtained through computational analysis.
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Introduction: Rational drug prescribing skills of interns remain bleak despite clinical pharmacology training during their second year, warranting the need for further training. This study was designed to evaluate the effectiveness of a short-structured learner-centric training program using the World Health Organization (WHO) guide to good prescribing in improving interns' knowledge of rational drug use and their rational drug prescribing skills.

Methods: This quasi-experimental study was implemented at a tertiary care teaching hospital in South India.

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A highly efficient and innovative method involving base-mediated oxidative annulation between 2-naphthols and phenylglyoxal monohydrate under visible light irradiation has been successfully developed. This method leads to the formation of oxygen-containing heterocyclic compounds, particularly hydroxy-naphthofuranone derivatives, encompassing a unique quaternary carbon center. An X-ray diffraction study has unambiguously confirmed the structure of one such derivative.

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Background: Inappropriate handling of biomedical waste (BMW) may pose serious threats to the health of patients and hospital personnel. Among all healthcare workers, staff nurses play a vital role in BMW management (BMWM). Thus, the present study aimed to determine the predictors of BMWM practices among staff nurses of a tertiary care teaching hospital in India.

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Graphene-based nanocomposites are developing as a new class of materials with several uses. The varied weight percentages of rGO on AgS catalysts were synthesized using a simple hydrothermal process and employed for the decomposition of anionic dye naphthol green B (NGB) under solar light. The reduced graphene oxide-based silver sulfide (rGO/AgS) nanoparticles were then examined using XRD, SEM, EDS, HR-TEM, XPS, UV-DRS, and PL analysis.

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A field study was conducted to investigate the persistence of foliar-applied thiamethoxam 25% WG at a rate of 25 g ai ha and chlorantraniliprole 18.5% SC at 30 g ai ha in various parts of rice plants, including whole grain rice, brown rice, bran, husk, straw, and cooked rice. Liquid Chromatography-Mass spectrometry/Mass spectrometry was used for sample analysis.

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Background: Cilnidipine is a fourth-generation calcium channel blocker that is clinically used to treat hypertension. It is a dihydropyridine that blocks L- and N-type calcium channels. The inhibitory effect of cilnidipine on isolated detrusor muscle contractility has not been studied.

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Article Synopsis
  • Good water quality is crucial for life, leading to increased focus on degrading organic dye wastes from textiles to protect the environment.
  • This research focuses on creating a ceramic-based nanomaterial catalyst, specifically a reduced graphene oxide-ZnS (rGO-ZnS) composite, to break down dye solutions when exposed to sunlight.
  • The study shows that the rGO-ZnS nanomaterial effectively degrades naphthol blue black dye (NBB) by 93.7% under direct sunlight, while also examining the impact of radical scavengers and the antibacterial properties of the catalyst.
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At present, nanotechnology field development makes a major role in photocatalysis. CdS-ZnMoO₄ (36.6 wt%) coupled nanophotocatalyst is synthesized using facile hydrothermal method.

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Background: Multi-drug resistant tuberculosis is on the rise, resulting in treatment failure. One potential reason for drug resistance is the substandard quality of manufactured antituberculous drugs. This study aims at finding out the difference in the quantity of isoniazid between government-supplied tablets and commercially available tablets.

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Background: Carbapenems are used for the treatment of serious infections caused by multidrug-resistant . Resistance to carbapenems in is mainly due to metallo-beta-lactamases (NDM, IMP, and VIM) and class D oxacillinase (OXA-48-like).

Aim And Objective: This study was undertaken to detect the genes encoding for carbapenemase in and to determine the clonal relatedness of selected isolates of producing NDM and OXA-48 by pulsed-field gel electrophoresis method (PFGE).

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Background: The carbapenemase-encoding genes, confer resistance to all the known beta-lactams and are encountered along with other beta-lactamase-encoding genes and/or 16S ribosomal RNA (rRNA)-methylating genes. The co-occurrence of and on a single plasmid is a rare occurrence.

Aim And Objective: The purpose of the study was to characterize the plasmids in isolates producing 16S rRNA methyltransferase along with , , and other resistance encoding genes.

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Purpose: This study was undertaken to characterise the virulence factors in clinical strains of Klebsiella pneumoniae and analyse their association with various infections caused and also to determine the association between virulence factors and antimicrobial resistance profile.

Materials And Methods: A total number of 370 clinically significant, non-duplicate isolates of K. pneumoniae isolated from both hospitalised patients and patients attending clinics were included in this study.

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Context: Avanafil is a smooth muscle relaxant that is clinically used to treat erectile dysfunction. It is an inhibitor of phosphodiesterase-5 (PDE5), the enzyme that catalyzes the metabolism of cyclic guanosine monophosphate (cGMP). The inhibitory effect of avanafil on isolated detrusor muscle contractility has not been studied.

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This study investigates the symbiotic effect of cetyltrimethylammonium bromide (CTAB) coupled with sonication of fruits and vegetable dregs (FVD) on disintegration and subsequent energy efficient methane production. The liquefaction of FVD experiments was conducted by varying dosage of surfactant from 0.001to 0.

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Background: () is an important nosocomial pathogen, and the emergence of multidrug resistance in these organisms limits the treatment options for serious infections caused by them. carbapenemase (KPC) is one of the clinically significant Class A beta-lactamases.

Aim And Objective: This study was aimed to detect the KPC and its coexistence with other beta-lactamases in .

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Background: causes both nosocomial and community-associated infections. Hypervirulent (hvKP), new variant of , can cause invasive infections in young healthy individuals as well as in the immunocompromised population. Hypervirulent strains frequently belong to capsular serotypes K1 or K2.

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The present study explored the disintegration potential of fruits and vegetable residue through sodium dodecyl sulphate (SDS) assisted sonic pretreatment (SSP). In SSP method, initially the biomass barrier (lignin) was removed using SDS at different dosage, subsequently it was sonically disintegrated. The effect of SSP were assessed based on dissolved organic release (DOR) of fruits and vegetable waste and specific energy input.

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In this article we report preparation of 5 wt% HoVO4 doped ZnO via template-free hydrothermal process and investigated its photocatalytic activity against azo dyes Rhodamine-B (Rh-B), Trypan Blue (TB) and Acid Black 1 (AB 1) in solar light irradiation. The as prepared HoVO4 doped ZnO was characterised by X-ray diffraction (XRD), Field emission scanning electron microscopy (FE-SEM), Field emission Transmission electron microscopy (FE-TEM), Brunauer-Emmett-Teller (BET) surface area measurements, X-ray photoelectron spectroscopy (XPS), Diffused reflectance (DRS) and Photoluminescence (PL) spectroscopy. The SEM images clearly indicate the formation of nanoparticles in the range of 20-50 nm.

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Context: Kv7 potassium channels are expressed in several types of smooth muscles and could mediate physiological responses in the tissues expressed. Flupirtine is an analgesic that acts by opening Kv7 potassium channels. It has been shown to inhibit the contractility of several types of isolated smooth muscle.

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