The prevalence of adolescent myopia is remarkably increasing. Previous studies have indicated that an unhealthy diet is a risk factor for myopia. However, the link between diet-related inflammation and myopia is unclear.
View Article and Find Full Text PDFThe higher efficiency of electro-fermentation in synthesizing medium-chain fatty acids (MCFAs) compared to traditional fermentation has been acknowledged. However, the functional mechanisms of electrode-biofilm enhancing MCFAs synthesis remain research gaps. To address this, this study proposed a continuous flow electrode-biofilm reactor for chain elongation (CE).
View Article and Find Full Text PDFBackground: Psychological capital has become a prominent focus in positive psychology, highlighting the positive influence of higher psychological capital on individuals. Self-directed learning ability is a fundamental skill for students, vital for enhancing academic performance and professional development, and is integral to the continuous learning process of nursing students. Recognizing the relationship between psychological capital and self-directed learning ability is crucial for the progress and development of undergraduate nursing students.
View Article and Find Full Text PDFPurpose: Hippocampal-avoidance whole-brain radiotherapy (HA-WBRT) planning can present challenges. This study examines the influence of head tilt angles on the dosimetric characteristics of target and organs at risk (OARs), aiming to identify the optimal tilt angle that yields optimal dosimetric outcomes using tomotherapy (TOMO).
Methods: Eight patients diagnosed with brain metastases underwent CT scans at five tilt angles: [0°, 10°), [10°, 20°), [20°, 30°), [30°, 40°), and [40°, 45°].
J Biomed Mater Res A
September 2024
Early healing of bone defects is still a clinical challenge. Many bone-filling materials have been studied, among which photocrosslinked alginate has received significant attention due to its good biocompatibility and morphological plasticity. Although it has been confirmed that photocrosslinked alginate can be used as an extracellular matrix for 3D cell culture, it lacks osteogenesis-related biological functions.
View Article and Find Full Text PDFPurpose: This study aimed to estimate the median effective dose of intrathecal isobaric ropivacaine without opioid required for adequate cesarean delivery anesthesia after epidural labor analgesia.
Methods: Patients aged 20-40 years with American Society of Anesthesiology scores of I-II, body mass index ≤ 36, who underwent emergency cesarean delivery after failed vaginal delivery with epidural analgesia of a duration ≤ 6 h were included in the study. After removal of the epidural used for labor analgesia, a new combined spinal epidural was performed, and a dose of intrathecal isobaric ropivacaine without opioid was administered.
Background: Dysregulated circular RNAs (circRNAs) are involved in osteoarthritis (OA) progression.
Objective: We aimed to explore the effect of hsa_circ_0044719 (circTRIM25) on the ferroptosis of chondrocytes.
Methods: Chondrocytes were treated with interleukin (IL)-1β to generate cell model.
Despite the increased research efforts aimed at understanding iron-based conductive materials (CMs) for facilitating chain elongation (CE) to produce medium chain fatty acids (MCFAs), the impact of these materials on microbial community functions and the adaptation mechanisms to their biotoxicity remain unclear. This study found that the supply of zero-valent iron (ZVI) and magnetite enhanced the MCFAs carbon-flow distribution by 26 % and 52 %, respectively. Metagenomic analysis revealed the upregulation of fatty acid metabolism, pyruvate metabolism and ABC transporters with ZVI and magnetite.
View Article and Find Full Text PDFThe electro-peroxone (EP) process encounters two inherent challenges in wastewater treatment: sluggish O/O transfer and substantial ozone waste. To overcome these limitations, we introduced micro-nano bubbles (MNBs) aeration to enhance O/O dissolution and diffusion, ultimately aiming to improve the removal of trace pharmaceutical contaminants from hospital wastewater. In the MNBs aeration system, the ozone transfer coefficient ranging from 0.
View Article and Find Full Text PDFBerberine (BBR) is a Chinese herb with antioxidant and anti-inflammatory properties. In a previous study, we found that BBR had a protective effect against light-induced retinal degeneration in BALB/c mice. The purinergic P2X7 receptor (P2X7R) plays a key role in retinal degeneration via inducing oxidative stress, inflammatory changes, and cell death.
View Article and Find Full Text PDFNeuro Endocrinol Lett
December 2023
Objective: To investigate the correlation between the urinary microalbumin/creatinine ratio (UACR) and the occurrence and severity of leukoaraiosis.
Methods: A total of 323 patients were retrospectively recruited. Demographic, clinical, and laboratory data were collected at the time of admission, and the UACR was calculated based on the levels of urinary microalbumin and creatinine.
Background: Mitsugumin 53 (MG53) is a membrane repair factor that is associated with acute myocardial infarction. This study aimed to investigate the effects of MG53 on cardiomyocyte injury and the posttranslational modification of MG53.
Methods: Cardiomyocyte injury was evaluated by enzyme-linked immunosorbent assay and flow cytometry.
Mid-infrared (MIR) pulsed lasers near a 3 µm waveband show great potential for the high absorption of water molecules and many important gas molecules. A passively -switched mode-locked (QSML) -doped fluoride fiber laser with a low laser threshold and high slope efficiency around a 2.8 µm waveband is reported.
View Article and Find Full Text PDFThe local coordination environment of catalytical moieties directly determines the performance of electrochemical energy storage and conversion devices, such as Li-O batteries (LOBs) cathode. However, understanding how the coordinative structure affects the performance, especially for non-metal system, is still insufficient. Herein, a strategy that introduces S-anion to tailor the electronic structure of nitrogen-carbon catalyst (SNC) is proposed to improve the LOBs performance.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
June 2023
Developing optical thermometer phosphors with high sensitivity, high signal discriminability and strong fluorescence intensity is ongoing. A dual-emitting thermochromic phosphor, LiScSiO:Ce, Tb, was successfully synthesized via solid-state reaction method. The crystal structure, electronic structure, luminescent performance and thermal luminescence behaviors as well as the luminescence mechanism of LiScSiO:Ce, Tb were systematically investigated.
View Article and Find Full Text PDFRegulating non-apoptotic cell death of cancer cells provides a promising strategy to overcome apoptosis resistance during cancer treatment. Lipids are essential components to exacerbate several non-apoptotic cell death pathways. In the present study, unsaturated fatty acid (UFA) liposomes prepared with linoleic acid, oleic acid, or α-linolenic acid have the potential to affect lipid metabolism.
View Article and Find Full Text PDFDeveloping nitridosilicate red phosphors under mild synthesis conditions is important for regulating the emission quality of white light-emitting diodes (WLEDs). Based on the thermodynamic theory and crystal structure chemistry for the synthesis of nitridosilicates, the Gibbs free energy variation of a hybrid system can be made more negative by reducing the proportion of SiN and increasing the proportion of MN and AlN, enabling the formation of new nitridosilicates under mild conditions. Therefore, a general chemical formula MSiAlN was proposed for the design of nitridosilicate red phosphors prepared under mild conditions, where M is an alkaline earth metal ion; > ; ≥ ; 1 ≤ ≤ 3; + 2 = 3 + 3; - = 2 + 2; and is a positive integer.
View Article and Find Full Text PDFThis study aimed to determine whether regular recruitment maneuvers (RMs) are essential for obese patients (OPs) undergoing elective laparoscopic bariatric surgery (LBS) during intraoperative ventilation with individualized positive end-expiratory pressure (PEEP). Patients were randomly assigned to two arms: the RM + PEEP arm consisted of individualized PEEP titrated by electrical impedance tomography (EIT) with two regular RMs and the PEEP arm consisted of individualized PEEP titrated by EIT without additional RMs. For these two arms together, EIT-guided PEEP varied among individuals.
View Article and Find Full Text PDFSaturable absorber (SA) based harmonic mode-locking (HML) techniques at 2 µm waveband are much less reported than those at 1.5 µm waveband, the maximum repetition rate of the harmonic pulse generated by such techniques at 2 µm waveband is also much lower than those generated at 1.5 µm waveband.
View Article and Find Full Text PDFCyan phosphors have attracted considerable attention in recent years as an indispensable component for realizing full-spectrum lighting. In this study, a novel nitride-based cyan-emitting phosphor Ca2BN2Cl:Eu2+ was successfully prepared. Its crystal structure refined by the Rietveld refinement reveals that Ca2BN2Cl is formed by a tight host lattice and the edge-sharing Ca(N,Cl)4 tetrahedrons along with multiple crystallographic Ca sites for Eu2+ ions to occupy, which corresponds to its broad emission band.
View Article and Find Full Text PDFExtracellular ATP and its ultimate degradation product adenosine are potent extracellular signaling molecules that elicit a variety of pathophysiological pathways in retina through the activation of P2 and P1 purinoceptors, respectively. Excessive build-up of extracellular ATP accelerates pathologic responses in retinal diseases, whereas accumulation of adenosine protects retinal cells against degeneration or inflammation. This mini-review focuses on the roles of ATP and adenosine in three types of blinding diseases including age-related macular degeneration (AMD), glaucoma, and diabetic retinopathy (DR).
View Article and Find Full Text PDFBackground: While the influence of meteorology on carbon monoxide (CO) poisoning has been reported, few data are available on the association between air pollutants and the prediction of CO poisoning. Our objective is to explore meteorological and pollutant patterns associated with CO poisoning and to establish a predictive model.
Results: CO poisoning was found to be significantly associated with meteorological and pollutant patterns: low temperatures, low wind speeds, low air concentrations of sulfur dioxide (SO) and ozone (O8h), and high daily temperature changes and ambient CO (r absolute value range: 0.
Background: Medical education in China is in a transitional period, from passive learning models to experiential education. We modified an experiential education method for radiology education. The aim of this study is to evaluate the effect of this method on undergraduate radiology education.
View Article and Find Full Text PDFThis study is designed to obtain recombinant human acetylcholinesterase (rhAChE) and apply it in screening acetylcholinesterase inhibitors. The rhAChE was overexpressed in HEK293 cells transfected by plasmid of pCMV-AChE with the cationic liposome and rhAChE was found to be secreted into cell culture medium. AChE activity was assayed according to modified Ellman method to obtain kinetic parameters.
View Article and Find Full Text PDFEffects of chromium-loaded chitosan nanoparticles (Cr-CNP) on growth performance, blood metabolites, immune traits, and tissue chromium in finishing pigs were investigated. A total of 160 crossbred barrows (66.06 ± 1.
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