Publications by authors named "Shannon Altpeter"
Article Synopsis
- Appendiceal mucinous neoplasms (AMNs) are complex tumors linked to pseudomyxoma peritonei, and the need for better objective biomarkers is evident as current prognostic systems have limitations.
- A study of 183 patients using next-generation sequencing (NGS) found that 98% had significant genomic alterations, especially in genes like TP53 and SMAD4, which correlated with worse clinicopathologic outcomes.
- The results indicated that patients with specific gene alterations had significantly lower overall survival rates, making genomic testing a valuable tool for enhancing patient prognosis and identifying those needing more intensive monitoring and treatment.
Introduction: Early recurrence (ER) is a significant challenge for patients with colorectal peritoneal metastases (CRPM) following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS HIPEC). Preoperative risk stratification for ER would improve preoperative decision making.
Methods: We conducted a retrospective study examining patients who underwent CRS HIPEC for CRPM from 2000 to 2018.