Microplastic pollution at Qilianyu, the largest green sea turtle nesting grounds in the northern South China Sea.

Microplastics, new persistent pollutants, have recently attracted considerable attention. When present in beach sediments, microplastics may adversely affect the nesting and hatching of sea turtles on beaches. In this study, we investigate microplastic pollution at Qilianyu (northeastern Xisha Islands), the largest known nesting ground for green sea turtles () in China.

The prevalence and clinical presentation of Hirschsprung's disease in preterm infants: a systematic review and meta-analysis.

Purpose: Hirschsprung's disease (HD) is a rare occurrence in premature infants, and the exact prevalence varying across studies. Thus, we conducted this study to determine the prevalence of and clinical presentation of HD in preterm infants.

Methods: The PubMed, EmBase, and Cochrane library databases were searched for eligible studies throughout May 2021.

Rapid authenticity testing of artificially bred green turtles () using microsatellite and mitochondrial DNA markers.

Sea turtles are threatened by climate change and human activity, and their global populations continue to decline sharply. The Chinese government encourages artificial breeding of sea turtles to reduce the use of wild populations. However, artificial breeding of sea turtles is still fairly difficult, and some facilities may illegally purchase wild turtle eggs and then sell incubated turtles by marketing them as artificially bred turtles, which adds another threat to an already endangered species.

The microplastic pollution in beaches that served as historical nesting grounds for green turtles on Hainan Island, China.

This study evaluated microplastic pollution in beaches that have served as historical nesting grounds for green turtles in Hainan Island, China and explored the sources of microplastic pollutants to conduct habitat restoration for sea turtles. The average abundance of the microplastics in the beach surface sediments was 2567.38 ± 2937.

Circulating exosomal microRNA-18a-5p accentuates intestinal inflammation in Hirschsprung-associated enterocolitis by targeting RORA.

The relevance of stem cell-derived exosomes has been implicated in necrotizing enterocolitis, while the involvement of serum-derived exosomes from children with Hirschsprung-associated enterocolitis (HAEC) in pathogenesis of HAEC remains unclear. This study set to identify the roles of exosomal microRNA (miR)-18a-5p from sera of HAEC patients in human-derived colonic epithelial NCM460 cells and in mice with HAEC. Exosomes were isolated from the sera of healthy children (Healthy-exo), patients with Hirschsprung's disease (HSCR) (HSCR-exo) or HAEC (HAEC-exo).

p53- and ROS-mediated AIF pathway involved in TGEV-induced apoptosis.

We previously demonstrated that transmissible gastroenteritis virus (TGEV) could induce apoptosis through caspase signaling. However, apoptosis was not completely prevented by caspases inhibitors, suggesting that there may be a caspase-independent pathway involved in TGEV-induced cell apoptosis. In this study, we investigated the regulation of apoptosis-inducing factor (AIF) on TGEV-induced apoptotic pathway.