Anti-P 200 pemphigoid - The most common floor binding subepidermal autoimmune bullous disease in a tertiary care center in south India.

Background: The pemphigoid group of diseases may present clinically and immunologically in a very similar fashion. Indirect immunofluorescence microscopy with readily available salt-split human skin in a BIOCHIP™ helps to classify these conditions as those with either with roof binding or floor binding of immunoreactants. Epidermolysis bullosa acquisita, anti-laminin 332 pemphigoid and anti-p200 pemphigoid show floor binding, while in the most frequent type of pemphigoid disease, bullous pemphigoid, epidermal side staining pattern is seen on salt-split skin Aims: The aim of the study was to detect the target antigens in sub-epidermal bullous diseases.

Allergic contact dermatitis to superglue.

Wigs are commonly used to cover baldness. A 28 year old male presented with itchy oozy eythematous lesions on the forehead where the wig was afixed to the scalp. Patch testing with indian standard seies and dental series revealed positivity to 2-hydroxy ethyl meta acrylate present in superglue.

Blister fluid immunofluorescence in a case of pemphigus vulgaris.

Indirect immunofluorescence with serum is used in the diagnosis of pemphigus. We report a case in whom blister fluid was used as the specimen for indirect immunofluorecscence.

Herpes misdiagnosed as pyoderma gangrenosum.

Retroviral infection is known to cause varied manifestation of any disease. We report a 27-year-old female who presented with non-healing painful ulcer in the left hand of 6 months' duration. The patient was diagnosed as pyoderma gangrenosum and treated with immunosuppressant drugs.