Publications by authors named "Shanmugapriya Saravanan"

Limited data exist on cytomegalovirus (CMV) antiviral treatment patterns among kidney transplant recipients (KTRs). Using United States Renal Database System registry data and Medicare claims (1 January 2011-31 December 2017), we examined CMV antiviral use in 22,878 KTRs who received their first KT from 2011 to 2016. Three-quarters of KTRs started CMV prophylaxis (85.

View Article and Find Full Text PDF

Background: The effects of chemotherapy dose intensity on patient outcomes in advanced cancer are not well understood. We studied the association between chemotherapy relative dose intensity (RDI) and overall survival (OS) among patients with advanced breast or ovarian cancer.

Patients And Methods: This retrospective cohort study included adults with advanced breast or ovarian cancer who received first-line myelosuppressive chemotherapy (January 2007 to December 2010) in US Oncology Network community practices.

View Article and Find Full Text PDF
Article Synopsis
  • A study examined how myelosuppressive chemotherapy regimens affect cancer patients, noting that common complications like febrile neutropenia can lead to delays and reduced doses, which may result in poorer survival rates.
  • Researchers analyzed data from over 16,000 patients receiving various chemotherapy regimens, finding that dose delays and reductions were frequent, with reduced relative dose intensity (RDI) highly variable among different patient groups and tumor types.
  • The findings suggest that many patients were treated with lower dose intensities than recommended, especially among older individuals, those who are obese, and those with limited daily activities.
View Article and Find Full Text PDF

Purpose. To assess epidemiology, treatment patterns, and outcomes of metastatic soft tissue sarcoma (mSTS) patients in USA community oncology practices. Methods.

View Article and Find Full Text PDF